CAS 127869-51-6

C-type natriuretic peptide

Description:

C-type natriuretic peptide (CNP) is a member of the natriuretic peptide family, which plays a crucial role in cardiovascular homeostasis. It is primarily produced in the endothelial cells of blood vessels and has significant effects on vasodilation, promoting the relaxation of smooth muscle cells and thereby lowering blood pressure. CNP is composed of a chain of amino acids, typically consisting of 22 to 53 residues, depending on the species. Its biological activity is mediated through specific receptors, primarily the natriuretic peptide receptor B (NPR-B), which activates guanylate cyclase, leading to increased levels of cyclic GMP in target cells. This signaling pathway contributes to various physiological processes, including inhibition of smooth muscle proliferation and modulation of renal function. CNP is also involved in bone growth and development, highlighting its importance beyond cardiovascular regulation. The substance is characterized by its relatively short half-life in circulation, necessitating precise regulation of its levels for effective physiological function.

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Synonyms:

• Natriuretic peptide, C-type
• Atriopeptin C (pig)
• C-Type Natriuretic Peptide (32-53) (Human, Porcine, Rat)

C-Type Natriuretic Peptide (32-53) (human, porcine, rat)

CAS: 127869-51-6

Bachem ID: 4095840.

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Purity: ≥ 95.2%

Color and Shape: White

Molecular weight: 2197.63

Ref: 01-4095840

C-Type Natriuretic Peptide (32-53) (human, porcine, rat)

CAS: 127869-51-6

Bachem ID: 4019911.

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Purity: 98.6%

Color and Shape: White

Molecular weight: 2197.63

Ref: 01-4019911

Rat C-type natriuretic peptide(1-22)

CAS: 127869-51-6

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 2197.6008

Ref: IN-DA009AWE

C-Type Natriuretic Peptide (CNP) (1-22), human

CAS: 127869-51-6

C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 2197.6

Ref: TM-TP1187

CNP-22 (Human, Porcine, Rat)

CAS: 127869-51-6

CNP-22 is a peptide that has been shown to activate ion channels, inhibit protein interactions, and bind to receptors. It has been used in research as an antibody activator, ligand inhibitor, and receptor antagonist. CNP-22 is a non-protein with a molecular weight of 714.

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Purity: Min. 95%

Molecular weight: 2,197.6 g/mol

Ref: 3D-PCT-4229-V

C-Type Natriuretic Peptide (32-53) acetate salt

CAS: 127869-51-6

C-type Natriuretic peptide is a peptide hormone that causes vasodilation, diuresis, and natriuresis. It is secreted by the heart and kidneys in response to volume overload. C-type Natriuretic peptide has been shown to cause fibrosis of the kidney as well as other tissues in mice. The binding of C-type Natriuretic peptide to its receptor activates cyclase, which converts ATP into cAMP. This leads to increased levels of cGMP, which causes smooth muscle relaxation and vasodilation.

Formula: C₉₃H₁₅₇N₂₇O₂₈S₃

Purity: Min. 95%

Molecular weight: 2,197.6 g/mol

Ref: 3D-FT110229