dl-2-Amino-4-methyl-5-phosphono-3-pentenoic acid, commonly referred to as AMPA, is a synthetic amino acid derivative that acts as a potent agonist of the glutamate receptor, specifically targeting the AMPA subtype. This compound is characterized by its unique structure, which includes an amino group, a phosphono group, and a pentenoic acid backbone. It is typically a white to off-white crystalline powder that is soluble in water, making it suitable for various biochemical applications. AMPA plays a significant role in neurobiology, particularly in studies related to synaptic transmission and plasticity, as it mimics the action of glutamate, the primary excitatory neurotransmitter in the central nervous system. Its ability to modulate neuronal activity makes it a valuable tool in research on learning, memory, and neurodegenerative diseases. Additionally, due to its phosphono group, it can participate in various chemical reactions, contributing to its utility in synthetic organic chemistry and pharmacological studies.

dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid

127910-31-0: dl-2-Amino-4-methyl-5-phosphono-3-pentenoic acid, commonly referred to as AMPA, is a synthetic amino acid derivative that acts as a potent agonist of the glutamate receptor, specifically targeting the AMPA subtype. This compound is characterized by its unique structure, which includes an amino group, a phosphono group, and a pentenoic acid backbone. It is typically a white to off-white crystalline powder that is soluble in water, making it suitable for various biochemical applications. AMPA plays a significant role in neurobiology, particularly in studies related to synaptic transmission and plasticity, as it mimics the action of glutamate, the primary excitatory neurotransmitter in the central nervous system. Its ability to modulate neuronal activity makes it a valuable tool in research on learning, memory, and neurodegenerative diseases. Additionally, due to its phosphono group, it can participate in various chemical reactions, contributing to its utility in synthetic organic chemistry and pharmacological studies.

3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-

CGP 37849

<p>CGP 37849: oral NMDA antagonist (Ki=35 nM), anticonvulsant, with antidepressant/anxiolytic effects.</p>

CAS 127910-31-0

dl-2-amino-4-methyl-5-phosphono-3-*pentenoic acid

3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, (3E)-

Ref: IN-DA000H8C

CGP 37849

Ref: 54-BUP02982

CGP 37849

Ref: TM-T7720