CAS 127985-21-1

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-7-iodo-5-methyl-6-oxo-, ethyl ester

Description:

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 5,6-dihydro-7-iodo-5-methyl-6-oxo-, ethyl ester, identified by CAS number 127985-21-1, is a complex organic compound characterized by its unique bicyclic structure that combines imidazole and benzodiazepine moieties. This compound typically exhibits properties associated with both heterocyclic and aromatic systems, which may contribute to its potential biological activity. The presence of the ethyl ester functional group suggests that it may have enhanced lipophilicity, potentially influencing its solubility and permeability in biological systems. The iodine substitution at the 7-position may impart specific reactivity or biological interactions, making it of interest in medicinal chemistry. Additionally, the carboxylic acid functionality indicates potential for further derivatization or interaction with biological targets. Overall, this compound's structural features suggest it may be investigated for pharmacological applications, particularly in the fields of neuropharmacology or as a scaffold for drug development.

Formula: C₁₅H₁₄IN₃O₃

Synonyms:

• Iomazenil
• Ro 16-0154

Iomazenil

CAS: 127985-21-1

Iomazenil is a benzodiazepine derivative that has been used as an antidote for benzodiazepine overdose. It binds to the GABA-A receptor and increases the rate of metabolism, which leads to increased blood flow to the brain. Iomazenil also has analytical applications in diagnosing hyperproliferative diseases such as cancer, by measuring the levels of metabolites in urine or blood samples. The drug can be used to measure metabolic rates and the activity index of caudate putamen cells. It also binds to receptors on mononuclear leukocytes and induces an increase in gamma-aminobutyric acid (GABA) production, which leads to cell death.

Formula: C₁₅H₁₄IN₃O₃

Purity: Min. 95%

Molecular weight: 411.19 g/mol

Ref: 3D-CFA98521

Iomazenil

CAS: 127985-21-1

Iomazenil is an antagonist and partial inverse agonist of benzodiazepine and potential therapy for alcohol abuse.

Formula: C₁₅H₁₄IN₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 411.19

Ref: TM-T25537