CAS 128-20-1: Pregnanolone
Description:Pregnanolone is a naturally occurring steroid and a neuroactive metabolite of progesterone, classified as a neurosteroid. It is characterized by its role in modulating the activity of neurotransmitter receptors, particularly GABA(A) receptors, which can influence mood, anxiety, and cognitive functions. Pregnanolone is a white crystalline solid at room temperature and is soluble in organic solvents such as ethanol and chloroform, but has limited solubility in water. Its molecular formula is C21H34O2, and it features a steroid backbone with a hydroxyl group, contributing to its biological activity. Pregnanolone is involved in various physiological processes, including the regulation of the menstrual cycle and the development of the central nervous system. Additionally, it has been studied for its potential therapeutic effects in conditions such as anxiety disorders and neurodegenerative diseases. Due to its neuroactive properties, it is of interest in pharmacological research, although its clinical applications are still being explored.
Formula:C21H34O2
InChI:InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1
InChI key:InChIKey=AURFZBICLPNKBZ-YZRLXODZSA-N
SMILES:O=C(C)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C
- Synonyms:
- (3Alpha)-3-Hydroxypregnan-20-One
- (3Alpha,5Beta)-3-Hydroxypregnan-20-One
- (3α,5β)-3-Hydroxypregnan-20-one
- 3-Alpha-Hydroxy-5-Beta-Pregnan-20-One
- 3-Deoxo-3α-hydroxy-5β-dihydroprogesterone
- 3-Hydroxypregnan-20-One
- 3alpha,5beta-Epimeric pregnanolone
- 3alpha-Hydroxy-5beta-pregnan-20-one
- 3alpha-Hydroxy-5beta-tetrahydroprogesterone
- 3α,5β-Pregnanolone
- See more synonyms
- 3α,5β-Tetrahydroprogesterone
- 3α-Hydroxy-20-oxo-5β-pregnane
- 3α-Hydroxy-5β,17β-pregnan-20-one
- 3α-Hydroxy-5β-pregnan-20-one
- 3α-Hydroxy-5β-tetrahydroprogesterone
- 5β-Pregnan-20-one, 3α-hydroxy-
- 5β-Pregnane-3α-ol-20-one
- Eltanolone
- Kabi 2213
- NSC 82867
- Pregnan-20-one, 3-hydroxy-, (3α,5β)-
- Pregnan-3alpha-ol-20-one
- Pregnan-3α-ol-20-one
- Pregnanolone
- Pregnanolone II
- Skf 6455
- U 2340
