CymitQuimica logo

CAS 128-45-0

:

Streptomycin B

Description:
Streptomycin B, with the CAS number 128-45-0, is an aminoglycoside antibiotic that is primarily derived from the bacterium Streptomyces griseus. It exhibits broad-spectrum antibacterial activity, particularly against gram-negative bacteria, and is often used in the treatment of tuberculosis and other infections. The compound is characterized by its ability to inhibit protein synthesis in bacteria by binding to the 30S ribosomal subunit, leading to misreading of mRNA and ultimately bacterial cell death. Streptomycin B is typically administered via injection due to its poor absorption from the gastrointestinal tract. It is important to note that, like other aminoglycosides, it can have nephrotoxic and ototoxic side effects, necessitating careful monitoring of renal function and hearing during treatment. The substance is also sensitive to degradation in the presence of certain conditions, such as high pH or heat, which can affect its stability and efficacy. Overall, Streptomycin B remains a crucial agent in the arsenal against resistant bacterial infections, particularly in combination therapies.
Formula:C27H49N7O17
InChI:InChI=1S/C27H49N7O17/c1-6-27(45,5-37)21(24(46-6)50-20-10(34-26(30)31)13(39)9(33-25(28)29)14(40)17(20)43)51-22-11(32-2)15(41)19(8(4-36)48-22)49-23-18(44)16(42)12(38)7(3-35)47-23/h5-24,32,35-36,38-45H,3-4H2,1-2H3,(H4,28,29,33)(H4,30,31,34)/t6-,7-,8-,9+,10-,11-,12+,13+,14-,15-,16-,17+,18-,19-,20+,21-,22-,23+,24-,27+/m0/s1
InChI key:InChIKey=HQXKELRFXWJXNP-ABOIPUQESA-N
SMILES:O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O[C@H]4O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@H](CO)O3
Synonyms:
  • 2,2'-(4-{[hexopyranosyl-(1->4)-2-deoxy-2-(methylamino)hexopyranosyl-(1->2)-5-deoxy-3-C-formylpentofuranosyl]oxy}-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine
  • <span class="text-smallcaps">D</smallcap>-Streptamine, O-β-<smallcap>D</smallcap>-mannopyranosyl-(1→4)-O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-
  • <span class="text-smallcaps">D</smallcap>-Streptamine, O-β-<smallcap>D</smallcap>-mannopyranosyl-(1→4)-O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-
  • Brn 0077587
  • D-Streptamine, O-beta-D-mannopyranosyl-(1.fwdarw.4)-O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1.fwdarw.4)-N,N'-bis(aminoiminomethyl)-
  • Mannosidostreptomycin
  • Mannosylstreptomycin
  • N'',N'''''-[(1S,2R,3R,4S,5R,6R)-2,4,5-trihydroxy-6-{[beta-D-mannopyranosyl-(1->4)-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]oxy}cyclohexane-1,3-diyl]diguanidine
  • O-β-<span class="text-smallcaps">D</smallcap>-Mannopyranosyl-(1→4)-O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</smallcap>-lyxofuranosyl-(1→4)-N<sup>1</sup>,N<sup>3</sup>-bis(aminoiminomethyl)-<smallcap>D</span>-streptamine
  • Streptomycin B
  • See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 2 products.