CAS 128-57-4
:Sennoside B
Description:
Sennoside B, with the CAS number 128-57-4, is a natural compound primarily derived from the leaves and pods of the Senna plant, particularly Senna alexandrina. It belongs to a class of compounds known as anthraquinones, which are characterized by their polycyclic aromatic structure. Sennoside B is recognized for its laxative properties, functioning as a stimulant laxative by promoting peristalsis in the intestines. It is often used in herbal medicine and over-the-counter laxative formulations. The compound is typically found in the form of a yellowish powder and is soluble in water, which facilitates its absorption and efficacy in the gastrointestinal tract. In addition to its laxative effects, Sennoside B has been studied for potential antioxidant and anti-inflammatory properties. However, its use should be approached with caution, as excessive consumption can lead to adverse effects such as abdominal cramping and diarrhea. Overall, Sennoside B is a significant compound in both traditional and modern medicinal practices, particularly in the treatment of constipation.
Formula:C42H38O20
InChI:InChI=1/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1
InChI key:InChIKey=IPQVTOJGNYVQEO-AIFLABODSA-N
SMILES:O=C1C=2C([C@@](C=3C1=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=CC3)([C@@]5(C=6C(C(=O)C=7C5=CC=CC7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)=C(O)C=C(C(O)=O)C6)[H])[H])=CC(C(O)=O)=CC2O
Synonyms:- (9R,9'S)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
- (9R,9′S)-5,5′-Bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid
- Nsc 112930
- Unii-F887D1637W
- [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (9R,9′S)-
- [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (R*,S*)-
- [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (R*,S*)-
- Sennoside B
- (9R,9′S)-5,5′-Bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid
- [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (9R,9′S)-
- SENNIDINE B(RG)
- Sennoside B std.
- SENNOSIDE B WITH HPLC
- (9S,9'R)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid
- PURSENNIDE
- (9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
- SENNOSIDE B hplc
- SENNOSIDE B(SH)
- [9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'S)-
- (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
- 9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-
- SENNOSIDE B(P)
- SENNOSIDE B 96.5+%
- GLYSENNIDE
- See more synonyms
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Found 16 products.
Sennoside B
CAS:Sennoside B analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C42H38O20Purity:(HPLC) ≥97%Color and Shape:PowderMolecular weight:862.75Sennoside B
CAS:<p>Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives</p>Formula:C42H38O20Color and Shape:Yellow PowderMolecular weight:862.19564[9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'S)-
CAS:Formula:C42H38O20Purity:98%Color and Shape:SolidMolecular weight:862.7391Sennoside B
CAS:Formula:C42H38O20Purity:>95.0%(HPLC)Color and Shape:White to Yellow to Yellow green powder to crystalMolecular weight:862.75Sennoside B
CAS:<p>Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.</p>Formula:C42H38O20Purity:92.85% - 98.92%Color and Shape:Light Yellow CrystalMolecular weight:862.74Sennoside b
CAS:Natural glycosideFormula:C42H38O20Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:862.75Sennoside B
CAS:<p>Sennoside B is a natural laxative derived from the leaves and pods of senna plants, specifically Cassia angustifolia and Cassia acutifolia. As an anthraquinone glycoside, its structure comprises a sugar moiety linked to an aglycone, which is responsible for its pharmacological activity. The mode of action of Sennoside B involves its biotransformation by gut bacteria in the colon, where it is converted into its active form, rhein anthrone. This active metabolite stimulates the mucosal lining of the colon and alters electrolyte transport across the intestinal epithelium. The result is increased peristaltic contractions and an augmented influx of water into the colon, leading to bowel movement facilitation.</p>Formula:C42H38O20Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:862.74 g/mol
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