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CAS 1280130-08-6

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Tenofovir disoproxil fumarate-s

Description:
Tenofovir disoproxil fumarate is an antiviral medication primarily used in the treatment of HIV and hepatitis B infections. It is a prodrug of tenofovir, which means it is metabolized in the body to its active form. The substance is characterized by its ability to inhibit the reverse transcriptase enzyme, thereby preventing viral replication. Tenofovir disoproxil fumarate is typically administered orally and is known for its favorable pharmacokinetic profile, including good bioavailability and a long half-life, allowing for once-daily dosing. The compound is a white to off-white powder, soluble in water, and has a molecular weight that reflects its complex structure. It is often formulated in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. Safety profiles indicate that it may cause side effects such as renal impairment and bone density loss, necessitating regular monitoring during treatment. Overall, Tenofovir disoproxil fumarate is a critical component of modern antiretroviral therapy.
Formula:C19H30N5O10P・C4H4O4
Synonyms:
  • (S)-(((1-(6-Amino-9H-Purin-9-Yl)Propan-2-Yloxy)Methyl)Phosphoryl)Bis(Oxy)Bis(Methylene) Isopropyl Dicarbonate
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