CAS 128107-47-1

fmoc-O-tert-butyl-D-serine

Description:

Fmoc-O-tert-butyl-D-serine is a protected amino acid commonly used in peptide synthesis. It features a phenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The tert-butyl group provides steric hindrance, enhancing the stability of the molecule and preventing unwanted reactions at the hydroxyl group of the serine residue. This compound is typically utilized in solid-phase peptide synthesis due to its compatibility with various coupling reagents and its ability to be easily deprotected under mild conditions. Fmoc-O-tert-butyl-D-serine is characterized by its relatively high solubility in organic solvents, making it suitable for various synthetic applications. Its chirality, indicated by the "D" in its name, is crucial for the biological activity of the resulting peptides. Overall, this compound is an essential building block in the field of medicinal chemistry and peptide research, facilitating the development of biologically active compounds.

Formula: C₂₂H₂₅NO₅

InChI: InChI=1/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m1/s1

SMILES: CC(C)(C)OC[C@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12

Synonyms:

• Fmoc-D-Ser(tBu)-OH
• Fmoc-D-Ser(But)-OH
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-serine
• N-Fmoc-O-tert-butyl-D-serine
• Fmoc-O-tert.butyl-D-serine
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-D-SERINE
• FMOC-D-SER(BUT)
• FMOC-O-T-BUTYL-D-SERINE
• FMOC-D-SERINE(TBU)-OH
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-D-SERINE
• N-α-Fmoc-O-tert-butyl-D-serine
• N-ALPHA-FMOC-O-T-BUTYL-D-SERINE
• N-FMOC-O-t-butyl-D-serine
• N-ALPHA-FMOC-O-TERT-BUTYL-D-SERINE
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-T-BUTYL-D-SERINE
• TIMTEC-BB SBB002936
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-D-SERINE
• FMOC-D-SERINE(O-T-BUTYL)
• n-(9-fluorenylmethoxycarbonyl)-o-tert-butyl-d-serine

N-Fmoc-O-tert-butyl-D-serine, 98%

CAS: 128107-47-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₂H₂₅NO₅

Purity: 98%

Molecular weight: 383.44

Ref: 02-H62439

Fmoc-D-Ser(tBu)-OH

CAS: 128107-47-1

Bachem ID: 4009509.

Formula: C₂₂H₂₅NO₅

Purity: 99.76%

Color and Shape: White

Molecular weight: 383.44

Ref: 01-4009509

D-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 128107-47-1

Formula: C₂₂H₂₅NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 383.4376

Ref: IN-DA000XT4

FMOC-L-Ser(tBu)-OH

CAS: 128107-47-1

FMOC-L-Ser(tBu)-OH

Formula: C₂₂H₂₅NO₅

Purity: 99%

Color and Shape: white to off-white solid

Molecular weight: 383.44g/mol

Ref: 54-OR54574

Fmoc-D-Ser(tBu)-OH

CAS: 128107-47-1

Formula: C₂₂H₂₅NO₅

Purity: (HPLC) ≥ 98.0%

Color and Shape: White powder

Molecular weight: 383.44

Ref: 7W-GM0291

Fmoc-D-Ser(tBu)-OH

CAS: 128107-47-1

M03384 - Fmoc-D-Ser(tBu)-OH

Formula: C₂₂H₂₅NO₅

Purity: 97%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 383.444

Ref: 10-M03384

Fmoc-D-Ser(tBu)-OH

CAS: 128107-47-1

Formula: C₂₂H₂₅NO₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 383.44

Ref: 3B-B5294

Fmoc-D-Ser(tBu)-OH

CAS: 128107-47-1

Formula: C₂₂H₂₅NO₅

Molecular weight: 383.4

Ref: ST-EA-CP-L28013

Fmoc-O-tert-butyl-D-serine

CAS: 128107-47-1

Fmoc-O-tert-butyl-D-serine is a synthetic, serine protease inhibitor. It has been shown to have antibacterial activity against gram-negative pathogens, such as Proteus vulgaris and Escherichia coli. Fmoc-O-tert-butyl-D-serine inhibits the influenza virus by blocking the cleavage of the M1 protein from the viral RNA strand. The molecule also has a matrix assisted laser desorption/ionization (MALDI) mass spectrometry detection method that can be used for identification of homologous proteins.

Formula: C₂₂H₂₅NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 383.44 g/mol

Ref: 3D-FF37561