CAS 128196-01-0

(+)-Citalopram

Description:

(+)-Citalopram, with the CAS number 128196-01-0, is a selective serotonin reuptake inhibitor (SSRI) primarily used in the treatment of major depressive disorder and anxiety disorders. It is characterized by its ability to increase serotonin levels in the brain, which can help improve mood and alleviate symptoms of depression. The compound is a chiral molecule, with the (+) designation indicating its specific enantiomeric form, which is believed to be more pharmacologically active than its counterpart. (+)-Citalopram is typically administered in oral form and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics involve extensive metabolism in the liver, primarily through cytochrome P450 enzymes, leading to various metabolites. Common side effects may include nausea, dry mouth, and changes in weight, among others. The substance has a relatively long half-life, allowing for once-daily dosing in clinical practice. Overall, (+)-Citalopram is recognized for its efficacy and safety profile in managing depressive and anxiety symptoms.

Formula: C₂₀H₂₁FN₂O

InChI: InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1

InChI key: InChIKey=WSEQXVZVJXJVFP-FQEVSTJZSA-N

SMILES: C(CCN(C)C)[C@@]1(C=2C(CO1)=CC(C#N)=CC2)C3=CC=C(F)C=C3

Synonyms:

• 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-
• 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (S)-
• (1R)-1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3H-isobenzofuran-5-carbonitrile
• (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate (1:1)
• (S)-(+)-CITALOPRAM OXALATE
• (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
• 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate (1:1)
• S-(+)-Citalopram
• S-(+)-Citalopram
• Escitalopram
• 1-(3-Dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

(S)-Citalopram Oxalate

CAS: 128196-01-0, 219861-08-2

Formula: C₂₀H₂₁FN₂O·C₂H₂O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 414.43

Ref: 3B-E0958

ESCITALOPRAM CRS

CAS: 128196-01-0

ESCITALOPRAM CRS

Formula: C₂₀H₂₁FN₂O

Color and Shape: White. Yellowish. Crystalline Powder.

Molecular weight: 324.3919

Ref: 41-Y0001844

5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-

CAS: 128196-01-0

Formula: C₂₀H₂₁FN₂O

Purity: 98%

Color and Shape: Liquid

Molecular weight: 324.3919

Ref: IN-DA000XU8

Escitalopram

CAS: 128196-01-0

Escitalopram

Purity: ≥90%

Molecular weight: 324.39g/mol

Ref: 54-BUP15016

(S)-Citalopram

CAS: 128196-01-0

Applications (S)-Citalopram is an inhibitor of serotonin (5-HT) uptake. Antidepressant.
References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977); Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000); Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001)

Formula: C₂₀H₂₁FN₂O

Color and Shape: Colourless To Light Yellow

Molecular weight: 324.39

Ref: TR-C505005

Escitalopram

Controlled Product

CAS: 128196-01-0

Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that is used for the treatment of major depressive disorder. Escitalopram binds to the serotonin transporter protein, which inhibits the reuptake of serotonin from the synaptic cleft and increases its concentration in the synaptic cleft. Escitalopram has been shown to be effective in treating depression and anxiety disorders. Escitalopram's antidepressant effects are statistically significant in comparison to placebo, but it is unclear if these effects are clinically significant. Escitalopram also has cardiac effects, including increased heart rate and blood pressure. The drug interacts with non-steroidal anti-inflammatory drugs, such as ibuprofen or aspirin, and can increase their effects on platelets and reduce their ability to prevent blood clots.

Formula: C₂₀H₂₁FN₂O

Purity: Min. 95 Area-%

Color and Shape: Colorless Clear Liquid

Molecular weight: 324.39 g/mol

Ref: 3D-FE102240

Escitalopram

CAS: 128196-01-0

Escitalopram (Seroplex), a serotonin inhibitor for depression, curbs alcohol intake and is favored over tricyclics for tardive dyskinesia.

Formula: C₂₀H₂₁FN₂O

Purity: 99.82%

Color and Shape: White Or White Crystalline Powder

Molecular weight: 324.39

Ref: TM-T0185