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CAS 128196-02-1

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(-)-Citalopram

Description:
(-)-Citalopram, with the CAS number 128196-02-1, is a selective serotonin reuptake inhibitor (SSRI) primarily used in the treatment of major depressive disorder and anxiety disorders. It is a chiral compound, with the (-)-enantiomer being the active form that exerts its therapeutic effects. The molecular formula of (-)-Citalopram is C20H21FN2O, and it features a phenyl ring, a piperazine moiety, and a fluorine atom, contributing to its pharmacological properties. The compound works by inhibiting the reuptake of serotonin in the brain, thereby increasing serotonin levels in the synaptic cleft, which is believed to enhance mood and alleviate symptoms of depression. (-)-Citalopram is typically administered orally and is known for its relatively favorable side effect profile compared to other antidepressants. It is important to note that, like all SSRIs, it may take several weeks to achieve its full therapeutic effect, and discontinuation should be managed carefully to avoid withdrawal symptoms.
Formula:C20H21FN2O
InChI:InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m1/s1
InChI key:InChIKey=WSEQXVZVJXJVFP-HXUWFJFHSA-N
SMILES:C(CCN(C)C)[C@]1(C=2C(CO1)=CC(C#N)=CC2)C3=CC=C(F)C=C3
Synonyms:
  • R-(-)-Citalopram
  • (R)-Citalopram
  • 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (R)-
  • 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1R)-
  • (1R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile
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