CAS 128219-76-1

N2-DMF-5'-O-DMT-2'-O-methylguanosine

CAS: 128219-76-1

N2-DMF-5'-O-DMT-2'-O-methylguanosine is a novel nucleoside analog that has antiviral, anticancer and immunomodulating properties. It is synthesized from 2′,3′-dideoxyadenosine 5′-monophosphate by the condensation of 2,6-dimethylaniline with methylguanosine 5′-monophosphate and 5,6-dimethylaniline. The modification of the guanine base in N2-DMF-5'-O-DMT-2'-O-methylguanosine to an O6 -methyl group results in increased affinity for the ribonucleotide reductase enzyme (RNR) and inhibition of DNA synthesis.

Formula: C₃₅H₃₈N₆O₇

Purity: Min. 95%

Molecular weight: 654.71 g/mol

Ref: 3D-ND08425