CAS 128219-84-1
:5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLINOSINE
Description:
5'-O-(Dimethoxytrityl)-2'-O-methylinosine is a modified nucleoside that plays a significant role in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a purine base, inosine, which is modified at the 2' position with a methyl group, enhancing its stability and resistance to enzymatic degradation. The 5' position is protected by a dimethoxytrityl (DMT) group, which is commonly used in solid-phase oligonucleotide synthesis to prevent premature reactions during the synthesis process. The presence of the DMT group allows for selective deprotection, facilitating the stepwise assembly of nucleic acid sequences. This compound is typically used in research and therapeutic applications, including the development of antisense oligonucleotides and RNA interference technologies. Its structural modifications contribute to improved solubility and bioavailability, making it a valuable tool in molecular biology and genetic engineering. Overall, 5'-O-(Dimethoxytrityl)-2'-O-methylinosine exemplifies the advancements in nucleoside chemistry aimed at enhancing the efficacy of nucleic acid-based therapies.
Formula:C32H32N4O7
Synonyms:- 5'-O-DMT-2'-O-Methyl-inosine
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Found 3 products.
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine
CAS:<p>Nucleoside Derivatives - 2’-Modified nucleosides,Protected nucleoside with NH2/OH open</p>Formula:C32H32N4O7Color and Shape:SolidMolecular weight:584.625'-O-DMT-2'-O-methylinosine
CAS:<p>5'-O-DMT-2'-O-methylinosine is a monophosphate nucleotide that has antiviral effects. It is synthesized from the synthetic nucleoside 5'-O-DMT-2'-deoxyuridine and 2'-O-methylinosine. The synthesis of 5'-O-DMT-2'-O-methylinosine is achieved through phosphoramidite chemistry, which produces a novel antiviral agent with high purity and quality. This compound has been shown to inhibit HIV replication in vitro, but further research is needed to determine its efficacy in vivo.</p>Formula:C32H32N4O7Purity:Min. 95%Molecular weight:584.63 g/mol


