CAS 1283000-43-0

MK-8033 (hydrochloride)

Description:

MK-8033 (hydrochloride) is a chemical compound that belongs to a class of molecules known for their potential therapeutic applications, particularly in the field of pharmacology. As a hydrochloride salt, it is typically more soluble in water than its base form, which can enhance its bioavailability. The compound is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. MK-8033 has been investigated for its role in modulating certain biological pathways, making it of interest in drug development. Its safety and efficacy profiles are evaluated through preclinical and clinical studies, focusing on its pharmacokinetics, pharmacodynamics, and potential side effects. As with many investigational drugs, detailed information regarding its mechanism of action, therapeutic uses, and comprehensive safety data may still be under research or subject to regulatory review. Overall, MK-8033 (hydrochloride) represents a promising candidate in the ongoing exploration of new therapeutic agents.

Formula: C₂₅H₂₂ClN₅O₃S

Synonyms:

• MK8033 HYDROCHLORIDE;MK 8033 HYDROCHLORIDE
• 3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)-5H-benzo[4,5]cyclohepta[1,2-b]pyridine-7-methanesulfonamide hydrochloride (1:1)
• MK-8033 (hydrochloride)
• 1-(3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide hydrochloride
• MK-8033 HCl

1-(3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide hydrochloride

CAS: 1283000-43-0

1-(3-(1-Methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide hydrochloride

Purity: 98%

Molecular weight: 508g/mol

Ref: 54-OR1063624

MK-8033 hydrochloride

CAS: 1283000-43-0

MK-8033 hydrochloride is a peptide that is used as a research tool for cell biology and pharmacology studies. It is an inhibitor of voltage-gated potassium channels, which are important for the transmission of nerve impulses. This drug has a high purity, and it has shown to be an activator of certain ion channels. MK-8033 hydrochloride binds to the N-terminal region of the alpha subunit of the acetylcholine receptor, which may increase its affinity for acetylcholine. MK-8033 hydrochloride has also been shown to inhibit ligand binding to receptors in cells, leading to inhibition of protein synthesis.

Formula: C₂₅H₂₂ClN₅O₃S

Purity: Min. 95%

Molecular weight: 507.99 g/mol

Ref: 3D-IBC00043

MK-8033 hydrochloride

CAS: 1283000-43-0

MK-8033 hydrochloride is an oral ATP-competitive c-Met/Ron inhibitor (IC50: c-Met 1nM, Ron 7nM), used for various cancers including NSCLC.

Formula: C₂₅H₂₂ClN₅O₃S

Color and Shape: Solid

Molecular weight: 507.99

Ref: TM-T12068