CymitQuimica logo

CAS 128312-51-6

:

Cinalukast

Description:
Cinalukast is a chemical compound classified as a leukotriene receptor antagonist, primarily used in the management of asthma and allergic rhinitis. It works by inhibiting the action of leukotrienes, which are inflammatory mediators that contribute to bronchoconstriction and mucus production. The molecular structure of Cinalukast includes a carboxylic acid functional group, which is essential for its biological activity. It is typically administered orally and is known for its relatively high bioavailability. Cinalukast exhibits a moderate half-life, allowing for once-daily dosing in therapeutic regimens. The compound is generally well-tolerated, with a side effect profile that may include headache, gastrointestinal disturbances, and potential liver enzyme elevations. As with other leukotriene receptor antagonists, it is important to monitor patients for any adverse reactions, particularly in those with pre-existing liver conditions. Overall, Cinalukast represents a valuable option in the pharmacological management of respiratory conditions, contributing to improved patient outcomes in asthma control.
Formula:C23H28N2O3S
InChI:InChI=1S/C23H28N2O3S/c1-3-23(4-2,22(27)28)14-20(26)24-18-10-5-7-16(13-18)11-12-21-25-19(15-29-21)17-8-6-9-17/h5,7,10-13,15,17H,3-4,6,8-9,14H2,1-2H3,(H,24,26)(H,27,28)/b12-11+
InChI key:InChIKey=BZMKNPGKXJAIDV-VAWYXSNFSA-N
SMILES:C(=C/C1=CC(NC(CC(C(O)=O)(CC)CC)=O)=CC=C1)\C2=NC(=CS2)C3CCC3
Synonyms:
  • (E)-4-[[3-[2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
  • 3'-((E)-2-(4-Cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid
  • 4-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}amino)-2,2-diethyl-4-oxobutanoic acid
  • 4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
  • Butanoic acid, 4-((3-(2-(4-cyclobutyl-2-thiazolyl)ethenyl)phenyl)amino)-2,2-diethyl-4-oxo-, (E)-
  • Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-
  • Cinalukast [USAN:INN]
  • Ro 24-5913
  • Unii-5E1O433Qai
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.