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CAS 128439-48-5

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altromycin C

Description:
Altromycin C is a natural antibiotic compound belonging to the class of macrolides, which are characterized by their large lactone rings. It is produced by certain strains of the bacterium Micromonospora. This compound exhibits antibacterial properties, particularly effective against a range of Gram-positive bacteria. Altromycin C's mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby disrupting the translation process. The structure of altromycin C includes multiple hydroxyl groups and a characteristic macrolide ring, contributing to its biological activity and solubility. It is important to note that, like other antibiotics, the use of altromycin C may lead to the development of resistance in bacterial populations if not used judiciously. Research into altromycin C continues to explore its potential therapeutic applications and the mechanisms underlying its efficacy against resistant bacterial strains. As with any antibiotic, proper understanding and handling are essential to maximize its benefits while minimizing adverse effects and resistance development.
Formula:C46H57NO17
InChI:InChI=1/C46H57NO17/c1-18-36(49)27(56-8)15-31(60-18)46(55,43(54)58-10)25-13-24-34(41-35(25)26(48)14-30(62-41)45(6)21(4)64-45)40(53)33-23(38(24)51)12-11-22(39(33)52)29-17-44(5,47-7)42(20(3)59-29)63-32-16-28(57-9)37(50)19(2)61-32/h11-14,18-21,27-29,31-32,36-37,42,47,49-50,52,55H,15-17H2,1-10H3
Synonyms:
  • methyl [2-(2,3-dimethyloxiran-2-yl)-11-hydroxy-10-{5-[(5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy]-4,6-dimethyl-4-(methylamino)tetrahydro-2H-pyran-2-yl}-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-5-yl](hydroxy)(5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)acetate (non-preferred name)
  • Altromycin C
  • Octonic acid, 3,7-anhydro-4,8-dideoxy-2-C-(2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-(2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-C-methyl-3-(methylamino)-alpha-L-lyxo-hexopyranosyl)-4H-anthra(1,2-b)pyran-5-yl)-5-O-methyl-, methyl ester
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