CAS 128446-35-5

β-Cyclodextrin, 2-hydroxypropyl ethers

Description:

β-Cyclodextrin, 2-hydroxypropyl ethers, is a modified derivative of β-cyclodextrin, which is a cyclic oligosaccharide composed of seven glucose units. This compound is characterized by the introduction of hydroxypropyl groups, enhancing its solubility in water and organic solvents compared to native β-cyclodextrin. The modification improves its ability to form inclusion complexes with various hydrophobic molecules, making it valuable in pharmaceutical formulations, food technology, and cosmetics. β-Cyclodextrin, 2-hydroxypropyl ethers exhibits low toxicity and is generally recognized as safe (GRAS) for use in food applications. Its ability to encapsulate and stabilize active ingredients enhances bioavailability and protects sensitive compounds from degradation. Additionally, this substance has applications in drug delivery systems, where it can improve the solubility and stability of poorly soluble drugs. Overall, β-Cyclodextrin, 2-hydroxypropyl ethers is a versatile compound with significant utility in various industries due to its unique properties and functional capabilities.

Formula: Unspecified

Synonyms:

• β-Cyclodextrin, 2-hydroxypropyl ethers

Hydroxypropyl-beta-cyclodextrin

CAS: 128446-35-5

Color and Shape: White to Almost white powder to crystal

Ref: 3B-H0979

(2-Hydroxypropyl)-β-cyclodextrin, MW ca 1250-1480

CAS: 128446-35-5

2-Hydroxypropyl)--cyclodextrin is used to enhance solubility of hydrophobic compounds by forming complex with them. This favors its usage in pharmaceutics, in the manufacturing of drugs. Beta- cyclodextrin and its methyl derivative is used to remove cholesterol from cultured cells. Many common c

Formula: C₄₄H₇₅O₃₆

Color and Shape: Powder, White

Molecular weight: 1180.05

Ref: 02-H31133

HYDROXYPROPYLBETADEX CRS

CAS: 128446-35-5

HYDROXYPROPYLBETADEX CRS

Formula: C₃H₆N₂O

Molecular weight: 86.0925

Ref: 41-Y0000186

Hydroxypropyl Betadex

CAS: 128446-35-5

Dextrins, derived from potato starch

Formula: C₄₂H₇₀O₃₅(C₃H₆O)xwherexNumberofsubstitutionsofhydroxypropylgroups

Color and Shape: White Powder

Molecular weight: 1541.54

Ref: 45-1329709

2-Hydroxypropyl-β-cyclodextrin

CAS: 128446-35-5

Formula: C₆₃H₁₁₂O₄₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 1541.5382

Ref: IN-DA000Y45

(2-Hydroxypropyl)-β-cyclodextrin

CAS: 128446-35-5

(2-Hydroxypropyl)-β-cyclodextrin

Purity: 98%

Color and Shape: Solid

Molecular weight: 0.00g/mol

Ref: 54-BICY1076

2-Hydroxypropyl-β-cyclodextrin, EP, USP grade

CAS: 128446-35-5

Color and Shape: White or almost white amorphous or crystalline powder

Molecular weight: N/A

Ref: 7W-GE5877

(2-Hydroxypropyl)-β-cyclodextrin

CAS: 128446-35-5

(2-Hydroxypropyl)-β-cyclodextrin

Formula: C₆₃H₁₁₂O₄₂

Purity: 98%

Color and Shape: Solid-Powder

Molecular weight: 1541.54

Ref: 54-BI4556

2-Hydroxypropyl-β-Cyclodextrin

CAS: 128446-35-5

2-Hydroxypropyl-β-Cyclodextrin

Formula: C₆₃H₁₁₂O₄₂

Purity: 97%

Color and Shape: Solid-Powder

Molecular weight: 1541.53817

Ref: 54-BIH6067

2-Hydroxypropyl-β-cyclodextrin

CAS: 128446-35-5

Color and Shape: White powder

Molecular weight: N/A

Ref: 7W-GE5756

2-Hydroxypropyl-β-cyclodextrin, USP grade

CAS: 128446-35-5

Color and Shape: White or almost white crystalline powder

Molecular weight: N/A

Ref: 7W-GE3201

HP-β-CD

CAS: 128446-35-5

HP-β-CD (HP-β-CD) is a widely used drug delivery vehicle to improve stability and bioavailability.

Formula: C₆₃H₁₁₂O₄₂

Purity: 98% - ≥98%

Color and Shape: White Solid

Molecular weight: 1541.547

Ref: TM-T19609

HP-β-CD

CAS: 128446-35-5

(2-Hydroxypropyl)-β-cyclodextrin

Purity: 99% 19.6-26.3% (-OCH2CHOHCH3)

Ref: IN-DG44359

ß-Cyclodextrin HPB

CAS: 128446-35-5

Ref: 4Z-S-082088

2-Hydroxypropyl-beta-cyclodextrin

Controlled Product

CAS: 128446-35-5

Applications 2-Hydroxypropyl-β-cyclodextrin (HBC) is a widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with 2-Hydroxypropyl-β-cyclodextrin. The number of 2-hydroxypropyl ranges from 5 to 14.
References Pitha, J. et al.: Int. J. Pharmacol., 29, 73 (1986); Frijink, H.W. et al.: Pharm. Res., 8, 380 (1991);

Formula: (C₆H₁₀O₅)n(C₃H₆O)

Color and Shape: Neat

Ref: TR-H952565

2-Hydroxypropyl-b-cyclodextrin

CAS: 128446-35-5

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formula: C₄₂Hn)O₃₅·(C₃H₇O)n

Purity: Min. 98.0 Area-%

Color and Shape: Powder

Ref: 3D-OH05393

Hydroxypropyl-B-Cyclodextrin (HPBCD) ExiPlus, Multi-Compendial, 98%

CAS: 128446-35-5

Purity: min. 98%

Color and Shape: White, Powder, Clear, Colourless

Ref: SR-56043