CAS 1284487-51-9

Benzenemethanamine, N-[(2,4-difluorophenyl)methyl]-2,4-difluoro-

Description:

Benzenemethanamine, N-[(2,4-difluorophenyl)methyl]-2,4-difluoro- is an organic compound characterized by its amine functional group and the presence of multiple fluorine substituents on the aromatic rings. The compound features a benzenemethanamine backbone, which is modified by a difluorophenyl group, indicating that it has two fluorine atoms attached to the phenyl ring at the 2 and 4 positions. This substitution can influence the compound's chemical reactivity, polarity, and overall stability. The presence of fluorine atoms typically enhances lipophilicity and can affect the compound's biological activity, making it of interest in pharmaceutical applications. The molecular structure suggests potential for hydrogen bonding due to the amine group, which may also play a role in its solubility and interaction with biological targets. Overall, this compound's unique structure and substituents contribute to its potential utility in various chemical and medicinal contexts.

Formula: C₁₄H₁₁F₄N

Synonyms:

• Benzenemethanamine, N-[(2,4-difluorophenyl)methyl]-2,4-difluoro-
• Cabotegravir Impurity 10
• N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine

Dolutegravir Impurity 33 HCl Salt

CAS: 1284487-51-9

Formula: C₁₄H₁₁F₄N

Molecular weight: 269.24

Ref: 4Z-D-093041

N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine

Controlled Product

CAS: 1284487-51-9

Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.
References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)

Formula: C₁₄H₁₁F₄N

Color and Shape: Neat

Molecular weight: 269.238

Ref: TR-D448188

Dolutegravir Impurity 39

CAS: 1284487-51-9

Formula: C₁₄H₁₁F₄N

Molecular weight: 269.24

Ref: ST-EA-CP-D24043