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CAS 128461-01-8

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altromycin D

Description:
Altromycin D is a natural antibiotic compound belonging to the class of macrolides, which are characterized by their large lactone rings. It is produced by certain strains of bacteria, specifically from the genus Streptomyces. Altromycin D exhibits antibacterial activity, primarily against Gram-positive bacteria, making it valuable in the field of medicinal chemistry and pharmacology. The compound's mechanism of action typically involves inhibition of protein synthesis by binding to the bacterial ribosome, thereby disrupting the translation process. Altromycin D is structurally related to other macrolides, featuring a complex polycyclic structure that contributes to its biological activity. Its unique chemical properties, including solubility and stability, are influenced by the presence of various functional groups within its molecular framework. Research into altromycin D continues to explore its potential therapeutic applications, resistance mechanisms, and the possibility of synthetic modifications to enhance its efficacy and reduce side effects. Overall, altromycin D represents an important area of study in the development of new antibiotics in response to rising antibiotic resistance.
Formula:C47H59NO17
InChI:InChI=1/C47H59NO17/c1-19-37(50)28(57-9)16-32(61-19)47(56,44(55)59-11)26-14-25-35(42-36(26)27(49)15-31(63-42)46(6)22(4)65-46)41(54)34-24(39(25)52)13-12-23(40(34)53)30-18-45(5,48(7)8)43(21(3)60-30)64-33-17-29(58-10)38(51)20(2)62-33/h12-15,19-22,28-30,32-33,37-38,43,50-51,53,56H,16-18H2,1-11H3
Synonyms:
  • Octonic acid, 3,7-anhydro-4,8-dideoxy-2-C-(2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-(2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-(dimethylamino)-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-4H-anthra(1,2-b)pyran-5-yl)-5-O-methyl-, methyl ester
  • Altromycin D
  • methyl [10-{4-(dimethylamino)-5-[(5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy]-4,6-dimethyltetrahydro-2H-pyran-2-yl}-2-(2,3-dimethyloxiran-2-yl)-11-hydroxy-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-5-yl](hydroxy)(5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)acetate (non-preferred name)
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