CAS 128470-15-5

Melarsomine

Description:

Melarsomine is an organoarsenic compound primarily used as an antiprotozoal medication, particularly in the treatment of heartworm disease in dogs. It is characterized by its ability to inhibit the growth of certain parasites, specifically Dirofilaria immitis, the causative agent of heartworm. Melarsomine is typically administered via injection and is known for its efficacy in eliminating adult heartworms. The compound has a complex structure that includes arsenic, which contributes to its pharmacological activity but also raises concerns regarding toxicity and safety. In terms of physical properties, melarsomine is a white to off-white crystalline powder that is soluble in water, allowing for its use in aqueous formulations. Its mechanism of action involves the disruption of cellular processes in the target organisms, leading to their death. Due to its arsenic content, careful handling and adherence to safety protocols are essential when using melarsomine, as it can pose health risks to humans and other non-target organisms.

Formula: C₁₃H₂₁AsN₈S₂

InChI: InChI=1/C13H21AsN8S2/c15-5-7-23-14(24-8-6-16)9-1-3-10(4-2-9)19-13-21-11(17)20-12(18)22-13/h1-4H,5-8,15-16H2,(H5,17,18,19,20,21,22)

InChI key: InChIKey=MGEOLZFMLHYCFZ-UHFFFAOYSA-N

SMILES: N(C=1N=C(N)N=C(N)N1)C2=CC=C([As](SCCN)SCCN)C=C2

Synonyms:

• Arsonodithious acid, [4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-, bis(2-aminoethyl) ester
• Arsonodithious acid, as-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-, bis(2-aminoethyl) ester
• Bis(2-Aminoethyl) {4-[(4,6-Diamino-1,3,5-Triazin-2-Yl)Amino]Phenyl}Arsonodithioite
• Melarsomina
• Melarsomina [INN-Spanish]
• Melarsomine [INN]
• Melarsominum
• Melarsominum [INN-Latin]
• Unii-374Gj0S41A
• bis(2-Aminoethyl) p-((4,6-diamino-s-triazin-2-yl)amino)dithiobenzenearsonite
• Melarsomine

Melarsomine

CAS: 128470-15-5

Melarsomine is a trivalent arsenic drug used to treat canine heartworm and other worms. It's key in related research.

Formula: C₁₃H₂₁AsN₈S₂

Color and Shape: Solid

Molecular weight: 428.41

Ref: TM-T38686

Melarsomine

CAS: 128470-15-5

Formula: C₁₃H₂₁AsN₈S₂

Molecular weight: 428.41

Ref: 4Z-M-279001

Melarsomine

CAS: 128470-15-5

Melarsomine is an anthelmintic medication, which is a synthetic arsenical compound sourced from the broader category of arsenic-based pharmaceuticals. It functions via the action of interfering with cellular proteins and enzymes essential for the survival of parasitic worms, specifically targeting the adult Dirofilaria immitis, the causative agent of heartworm disease in canines.

Formula: C₁₃H₂₁AsN₈S₂

Purity: Min. 95%

Molecular weight: 428.4 g/mol

Ref: 3D-FM180297