CAS 128470-16-6

(-)-Arbutamine

Description:

(-)-Arbutamine, with the CAS number 128470-16-6, is a chiral compound that belongs to the class of phenethylamines. It is characterized by its specific stereochemistry, which contributes to its biological activity. This substance is known for its potential use as a cardiovascular agent, particularly in the treatment of conditions such as heart failure and arrhythmias. (-)-Arbutamine acts primarily as a beta-adrenergic agonist, which means it stimulates beta-adrenergic receptors, leading to increased heart rate and myocardial contractility. The compound is typically administered in a controlled manner due to its potent effects on the cardiovascular system. Its solubility and stability in various solvents can vary, influencing its formulation in pharmaceutical applications. As with many pharmacologically active compounds, understanding its pharmacokinetics, including absorption, distribution, metabolism, and excretion, is crucial for its therapeutic use. Safety and efficacy profiles are also essential considerations in clinical settings, necessitating thorough research and regulatory approval before widespread use.

Formula: C₁₈H₂₃NO₄

InChI: InChI=1S/C18H23NO4/c20-15-7-4-13(5-8-15)3-1-2-10-19-12-18(23)14-6-9-16(21)17(22)11-14/h4-9,11,18-23H,1-3,10,12H2/t18-/m0/s1

InChI key: InChIKey=IIRWWTKISYTTBL-SFHVURJKSA-N

SMILES: [C@@H](CNCCCCC1=CC=C(O)C=C1)(O)C2=CC(O)=C(O)C=C2

Synonyms:

• 1,2-Benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-
• 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-
• 1,2-Benzenediol, 4-[1-hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-, (R)-
• 4-(1-Hydroxy-2-{[4-(4-Hydroxyphenyl)Butyl]Amino}Ethyl)Benzene-1,2-Diol
• 4-[(1R)-1-Hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-1,2-benzenediol
• (-)-Arbutamine
• Arbutamine

4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol

CAS: 128470-16-6

Formula: C₁₈H₂₃NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 317.3795

Ref: IN-DA000Y4Z

Arbutamine

CAS: 128470-16-6

Arbutamine

Purity: ≥95%

Molecular weight: 317.38g/mol

Ref: 54-BUP00443

Arbutamine

Controlled Product

CAS: 128470-16-6

Applications Arbutamine is a cardiac stimulant. Arbutamine stimulates adrenergic receptors.
References Sinusas, A., et al.: J. Nucl. Med., 35, 664 (1994); Sansoy, V., et al.: Circulation, 92, 994 (1995); Elhendy, A., et al.: Eur. J. Nucl. Med., 23, 1354 (1996);

Formula: C₁₈H₂₃NO₄

Color and Shape: Neat

Molecular weight: 317.38

Ref: TR-A766300

Arbutamine-d6

Controlled Product

CAS: 128470-16-6

Formula: C₁₈D₆H₁₇NO₄

Color and Shape: Neat

Molecular weight: 323.416

Ref: TR-A766302

Arbutamine

CAS: 128470-16-6

Arbutamine (GP 21213) is a β-adrenoceptor agonist with alpha-1-sympathomimetic activity that can be used to study cardiac stress.

Formula: C₁₈H₂₃NO₄

Purity: 95.06%

Color and Shape: Solid

Molecular weight: 317.38

Ref: TM-T10364