CAS 128470-16-6: (-)-Arbutamine
Description:(-)-Arbutamine, with the CAS number 128470-16-6, is a chiral compound that belongs to the class of phenethylamines. It is characterized by its specific stereochemistry, which contributes to its biological activity. This substance is known for its potential use as a cardiovascular agent, particularly in the treatment of conditions such as heart failure and arrhythmias. (-)-Arbutamine acts primarily as a beta-adrenergic agonist, which means it stimulates beta-adrenergic receptors, leading to increased heart rate and myocardial contractility. The compound is typically administered in a controlled manner due to its potent effects on the cardiovascular system. Its solubility and stability in various solvents can vary, influencing its formulation in pharmaceutical applications. As with many pharmacologically active compounds, understanding its pharmacokinetics, including absorption, distribution, metabolism, and excretion, is crucial for its therapeutic use. Safety and efficacy profiles are also essential considerations in clinical settings, necessitating thorough research and regulatory approval before widespread use.
Formula:C18H23NO4
InChI:InChI=1S/C18H23NO4/c20-15-7-4-13(5-8-15)3-1-2-10-19-12-18(23)14-6-9-16(21)17(22)11-14/h4-9,11,18-23H,1-3,10,12H2/t18-/m0/s1
InChI key:InChIKey=IIRWWTKISYTTBL-SFHVURJKSA-N
SMILES:OC1=CC=C(C=C1)CCCCNCC(O)C2=CC=C(O)C(O)=C2
- Synonyms:
- 1,2-Benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-
- 1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-
- 1,2-Benzenediol, 4-[1-hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-, (R)-
- 4-(1-Hydroxy-2-{[4-(4-Hydroxyphenyl)Butyl]Amino}Ethyl)Benzene-1,2-Diol
- 4-[(1R)-1-Hydroxy-2-[[4-(4-hydroxyphenyl)butyl]amino]ethyl]-1,2-benzenediol
- (-)-Arbutamine
- Arbutamine