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CAS 128496-20-8

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1-(2,3-dideoxy-2,3-difluoroarabinofuranosyl)cytosine

Description:
1-(2,3-Dideoxy-2,3-difluoroarabinofuranosyl)cytosine, with the CAS number 128496-20-8, is a nucleoside analog that features a modified sugar moiety and a cytosine base. This compound is characterized by the presence of two fluorine atoms at the 2' and 3' positions of the arabinofuranosyl sugar, which contributes to its unique properties and potential biological activity. The modifications in the sugar structure can influence the compound's ability to interact with nucleic acid synthesis pathways, making it of interest in antiviral and anticancer research. The presence of the dideoxy group indicates that it lacks hydroxyl groups at the 2' and 3' positions, which is significant for its mechanism of action, as it may inhibit viral replication by terminating the elongation of nucleic acid chains. This compound is typically studied for its pharmacological properties and potential therapeutic applications, particularly in the context of viral infections and cancer treatment. Its stability, solubility, and bioavailability are also key characteristics that are evaluated in research settings.
Formula:C9H11F2N3O3
InChI:InChI=1/C9H11F2N3O3/c10-6-4(3-15)17-8(7(6)11)14-2-1-5(12)13-9(14)16/h1-2,4,6-8,15H,3H2,(H2,12,13,16)/t4-,6-,7+,8-/m1/s1
Synonyms:
  • 1-(2,3-Dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)cytosine
  • 1-Ddfac
  • 4-Amino-1-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)-2(1H)-pyrimidinone
  • 2(1H)-Pyrimidinone, 4-amino-1-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)-
  • 2',3'-Dideoxy-2',3'-Difluorocytidine
  • 4-amino-1-(2,3-dideoxy-2,3-difluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
  • 1-(2,3-Dideoxy-2,3-difluoroarabinofuranosyl)cytosine
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