CAS 128607-22-7: Ospemifene

Description: Ospemifene is a selective estrogen receptor modulator (SERM) primarily used in the treatment of dyspareunia, a condition characterized by painful intercourse due to vaginal atrophy associated with menopause. As a non-steroidal compound, it exhibits tissue-selective estrogenic activity, meaning it can mimic estrogen in certain tissues while blocking its effects in others. Ospemifene is known for its ability to promote vaginal and vulvar health by enhancing the thickness and elasticity of vaginal tissue, thereby alleviating discomfort. The substance has a relatively low bioavailability and is metabolized in the liver, with its pharmacokinetics influenced by various factors, including age and liver function. Common side effects may include hot flashes, vaginal discharge, and potential risks associated with estrogen therapy, such as thromboembolic events. Ospemifene's unique mechanism of action and its targeted approach make it a significant option for managing menopausal symptoms, particularly in women who cannot or prefer not to use traditional hormone replacement therapies.

Formula: C₂₄H₂₃ClO₂

InChI: InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-

InChI key: InChIKey=LUMKNAVTFCDUIE-VHXPQNKSSA-N

SMILES: ClCCC(C=1C=CC=CC1)=C(C=2C=CC=CC2)C3=CC=C(OCCO)C=C3

Synonyms:

• 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]ethanol
• 2-[4-[4-Chloro-1,2-diphenyl-1(Z)-butenyl]phenoxy]ethanol
• 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethanol
• Ethanol, 2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-, (Z)-
• Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-
• Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy]-
• FC-1271a
• Fc 1271
• Osphena
• Senshio

Ospemifene

CAS: 128607-22-7

• Formula: C₂₄H₂₃ClO₂
• Purity: >98.0%(GC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 378.90

Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-

CAS: 128607-22-7

• Formula: C₂₄H₂₃ClO₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 378.8912

Ospemifene

CAS: 128607-22-7

• Formula: C₂₄H₂₃ClO₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 378.90

Ospemifene-d4

CAS: 128607-22-7

• Formula: C₂₄H₁₉D₄ClO₂
• Color and Shape: Off-White Solid
• Molecular weight: 382.92

Ospemifene

CAS: 128607-22-7

Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for …

• Formula: C₂₄H₂₃ClO₂
• Purity: 99.73%
• Color and Shape: Solid
• Molecular weight: 378.89

Ospemifene-d4

CAS: 128607-22-7

Applications Ospemifene-d4 is the isotope labelled analog of Ospemifene (O703000). Ospemifene is used to treat …

• Formula: C₂₄D₄H₁₉ClO₂
• Color and Shape: Neat
• Molecular weight: 382.916

Ospemifene

CAS: 128607-22-7

Applications Ospemifene is used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) …

• Formula: C₂₄H₂₃ClO₂
• Color and Shape: White To Off-White
• Molecular weight: 378.89

Ospemifene

CAS: 128607-22-7

Please enquire for more information about Ospemifene including the price, delivery time and more detailed …

• Formula: C₂₄H₂₃ClO₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 378.89 g/mol

Ospemifene-13C2,d4

CAS: 128607-22-7

• Formula: C₂C₂₂D₄H₁₉ClO₂
• Color and Shape: Neat
• Molecular weight: 384.901

Ospemifene-d4

CAS: 128607-22-7

Applications Ospemifene-d4 is the isotope labelled analog of Ospemifene (O703000). Ospemifene is used to treat …

• Formula: C₂₄D₄H₁₉ClO₂
• Color and Shape: Neat
• Molecular weight: 382.916