CAS 128607-22-7
:Ospemifene
Description:
Ospemifene is a selective estrogen receptor modulator (SERM) primarily used in the treatment of dyspareunia, a condition characterized by painful intercourse due to vaginal atrophy associated with menopause. As a non-steroidal compound, it exhibits tissue-selective estrogenic activity, meaning it can mimic estrogen in certain tissues while blocking its effects in others. Ospemifene is known for its ability to promote vaginal and vulvar health by enhancing the thickness and elasticity of vaginal tissue, thereby alleviating discomfort. The substance has a relatively low bioavailability and is metabolized in the liver, with its pharmacokinetics influenced by various factors, including age and liver function. Common side effects may include hot flashes, vaginal discharge, and potential risks associated with estrogen therapy, such as thromboembolic events. Ospemifene's unique mechanism of action and its targeted approach make it a significant option for managing menopausal symptoms, particularly in women who cannot or prefer not to use traditional hormone replacement therapies.
Formula:C24H23ClO2
InChI:InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
InChI key:InChIKey=LUMKNAVTFCDUIE-VHXPQNKSSA-N
SMILES:C(=C(/CCCl)\C1=CC=CC=C1)(\C2=CC=C(OCCO)C=C2)/C3=CC=CC=C3
Synonyms:- 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]ethanol
- 2-[4-[4-Chloro-1,2-diphenyl-1(Z)-butenyl]phenoxy]ethanol
- 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethanol
- Ethanol, 2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-, (Z)-
- Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-
- Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy]-
- FC-1271a
- Fc 1271
- Osphena
- Senshio
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Found 10 products.
Ospemifene
CAS:Formula:C24H23ClO2Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:378.90Ospemifene
CAS:<p>Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.</p>Formula:C24H23ClO2Purity:99.95%Color and Shape:SolidMolecular weight:378.89Ospemifene-d4
CAS:Controlled Product<p>Applications Ospemifene-d4 is the isotope labelled analog of Ospemifene (O703000). Ospemifene is used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Formula:C24D4H19ClO2Color and Shape:NeatMolecular weight:382.916Ospemifene
CAS:Controlled Product<p>Applications Ospemifene is used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Formula:C24H23ClO2Color and Shape:White To Off-WhiteMolecular weight:378.89Ospemifene
CAS:Controlled Product<p>2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]ethanol is a selective estrogen receptor modulator that has been shown to inhibit the growth of breast cancer cells in mice. It binds to the estrogen receptor (ER) and inhibits its transcriptional activity by competing with estradiol for binding. 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]ethanol can be used as a postmenopausal hormonal therapy in women who are at an increased risk for breast cancer. This drug has been shown to have genotoxic activity and may cause dyspareunia and carcinogenic potential.</p>Formula:C24H23ClO2Purity:Min. 95%Color and Shape:PowderMolecular weight:378.89 g/molOspemifene-13C2,d4
CAS:Controlled ProductFormula:C2C22D4H19ClO2Color and Shape:NeatMolecular weight:384.901Ospemifene-d4
CAS:Controlled Product<p>Applications Ospemifene-d4 is the isotope labelled analog of Ospemifene (O703000). Ospemifene is used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Formula:C24D4H19ClO2Color and Shape:NeatMolecular weight:382.916Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-
CAS:Formula:C24H23ClO2Purity:98%Color and Shape:SolidMolecular weight:378.8912
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