CAS 1286427-93-7

DideMethyl CitalopraM-d6 HydrobroMide

Description:

DideMethyl CitalopraM-d6 HydrobroMide, with the CAS number 1286427-93-7, is a deuterated analog of the selective serotonin reuptake inhibitor (SSRI) citalopram. This compound is characterized by the presence of deuterium atoms, which are isotopes of hydrogen, replacing certain hydrogen atoms in the molecular structure. This modification enhances its stability and can facilitate studies in pharmacokinetics and metabolism due to the distinct mass of deuterium. The hydrobroMide form indicates that the compound is in a salt form, which can influence its solubility and bioavailability. As a pharmaceutical substance, it is primarily investigated for its potential effects on serotonin levels in the brain, making it relevant in the treatment of depression and anxiety disorders. The deuterated version may also be used in research settings to trace metabolic pathways or to improve the understanding of the drug's mechanism of action. Overall, DideMethyl CitalopraM-d6 HydrobroMide serves as a valuable tool in both clinical and research applications within the field of medicinal chemistry.

Formula: C₁₈H₁₈BrFN₂O

Synonyms:

• [2H6]- Didemethyl Citalopram Hydrobromide
• DideMethyl CitalopraM-d6 HydrobroMide

Didemethyl Citalopram-d6 Hydrobromide

Controlled Product

CAS: 1286427-93-7

Applications Didemethyl Citalopram-d6 Hydrobromide is the labeled analogue of Didemethyl Citalopram Hydrobromide (D439480), a metabolite of Citalopram (C505000), an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.
References Kugelberg, F.C., et al.: J. Anal. Toxicol., 28, 631 (2004); Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977); Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000); Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001)

Formula: C₁₈H₁₂D₆BrFN₂O

Color and Shape: Neat

Molecular weight: 383.29

Ref: TR-D439482