CAS 1286632-72-1

N-Demethyl Trimebutine-d5 Hydrochloride

Description:

N-Demethyl Trimebutine-d5 Hydrochloride is a deuterated derivative of trimebutine, a medication primarily used as an antispasmodic agent in the treatment of gastrointestinal disorders. The "d5" in its name indicates that it contains five deuterium atoms, which are isotopes of hydrogen, replacing regular hydrogen atoms in the molecular structure. This modification is often utilized in research to trace metabolic pathways or to enhance the stability of the compound. The hydrochloride form indicates that the substance is a salt, which typically improves its solubility in water. N-Demethyl Trimebutine-d5 Hydrochloride retains the pharmacological properties of trimebutine, acting on opioid receptors and modulating gastrointestinal motility. Its characteristics include a specific molecular weight and structure that can be analyzed using techniques such as NMR spectroscopy, mass spectrometry, and chromatography. As a research chemical, it is primarily used in pharmacokinetic studies and may not be widely available for clinical use. Safety and handling precautions should be observed, as with any chemical substance.

Formula: C₂₁H₂₈ClNO₅

Synonyms:

• [2H5]-N-Demethyl Trimebutine Hydrochloride
• N-Demethyl Trimebutine-d5 Hydrochloride

N-Demethyl Trimebutine-d5 Hydrochloride

Controlled Product

CAS: 1286632-72-1

Applications The main bioactive labelled metabolite of Trimebutine.
References Miura, Y., et al.: Drug Metab. Dispos., 17, 455 (1989), Xue, L., et al.: Eur. J. Pharmacol., 294, 75 (1995), Roman, F., et al.: J. Pharmacol. Exp. Ther., 289, 1391 (1999), Kayser, V., et al.: Life Sci., 66, 433 (2000),

Formula: C₂₁H₂₂D₅NO₅·HCl

Color and Shape: Neat

Molecular weight: 414.93

Ref: TR-D231342