Suc-Ala-Gln-Pro-Phe-pNA, also known as Succinyl-Ala-Gln-Pro-Phe-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays, particularly for the study of proteolytic enzymes. This compound features a sequence of amino acids, including alanine (Ala), glutamine (Gln), proline (Pro), and phenylalanine (Phe), linked to a p-nitroanilide (pNA) moiety, which serves as a chromogenic indicator. The succinyl group enhances the solubility and stability of the peptide in aqueous solutions. Upon cleavage by specific proteases, the release of pNA results in a measurable color change, allowing for quantitative analysis of enzyme activity. The characteristics of this compound include its role as a substrate in enzyme kinetics studies, its ability to provide a colorimetric response, and its utility in various biochemical research applications. Additionally, its stability and specificity make it a valuable tool in the study of proteolytic pathways and enzyme inhibition.

Suc-Ala-Gln-Pro-Phe-pNA

128822-33-3: Suc-Ala-Gln-Pro-Phe-pNA, also known as Succinyl-Ala-Gln-Pro-Phe-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays, particularly for the study of proteolytic enzymes. This compound features a sequence of amino acids, including alanine (Ala), glutamine (Gln), proline (Pro), and phenylalanine (Phe), linked to a p-nitroanilide (pNA) moiety, which serves as a chromogenic indicator. The succinyl group enhances the solubility and stability of the peptide in aqueous solutions. Upon cleavage by specific proteases, the release of pNA results in a measurable color change, allowing for quantitative analysis of enzyme activity. The characteristics of this compound include its role as a substrate in enzyme kinetics studies, its ability to provide a colorimetric response, and its utility in various biochemical research applications. Additionally, its stability and specificity make it a valuable tool in the study of proteolytic pathways and enzyme inhibition.

<p>Suc-Ala-Gln-Pro-Phe-pNA is a peptide that is composed of 18 amino acids. This peptide has a molecular weight of 2,812. It has been shown to have biochemical activity in vitro and in vivo. Suc-Ala-Gln-Pro-Phe-pNA is an erythropoietin receptor agonist that has shown homologous sequences with tyrosine kinase receptors and collagen. This protein was expressed in the endoplasmic reticulum, cytosol, and mitochondria of cells. The enzyme phosphatase hydrolyzed the peptide during incubation with calf thymus DNA.</p>

CAS 128822-33-3

Suc-Ala-Gln-Pro-Phe-pNA

Suc-Ala-Gln-Pro-Phe-pNA

Ref: 3D-FS110763