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CAS 128914-46-5

:

(5Z,8Z,11Z,14Z)-16-Hydroxy-5,8,11,14-eicosatetraenoic acid

Description:
(5Z,8Z,11Z,14Z)-16-Hydroxy-5,8,11,14-eicosatetraenoic acid, commonly known as 16-hydroxyeicosatetraenoic acid (16-HETE), is a polyunsaturated fatty acid that plays a significant role in various biological processes. It is derived from arachidonic acid and is involved in the metabolism of eicosanoids, which are crucial for inflammatory responses and cellular signaling. This compound exhibits anti-inflammatory properties and is implicated in the regulation of vascular functions, cell proliferation, and apoptosis. Structurally, it features multiple double bonds in its carbon chain, contributing to its reactivity and interactions with biological membranes. The presence of a hydroxyl group enhances its solubility in polar solvents and influences its biological activity. 16-HETE is also studied for its potential roles in various diseases, including cardiovascular disorders and cancer. Its synthesis and metabolism are regulated by specific enzymes, making it a target for therapeutic interventions aimed at modulating inflammatory responses. Overall, 16-HETE is an important lipid mediator with diverse physiological implications.
Formula:C20H32O3
InChI:InChI=1/C20H32O3/c1-2-3-16-19(21)17-14-12-10-8-6-4-5-7-9-11-13-15-18-20(22)23/h4-5,8-11,14,17,19,21H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14-
InChI key:InChIKey=JEKNPVYFNMZRJG-UFINWASNNA-N
SMILES:C(\C/C=C\C/C=C\C/C=C\CCCC(O)=O)=C\C(CCCC)O
Synonyms:
  • 5,8,11,14-Eicosatetraenoic acid, 16-hydroxy-, (all-Z)-
  • 16-HETE
  • 5,8,11,14-Eicosatetraenoic acid, 16-hydroxy-, (5Z,8Z,11Z,14Z)-
  • (5Z,8Z,11Z,14Z)-16-Hydroxy-5,8,11,14-eicosatetraenoic acid
  • See more synonyms
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