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CAS 128914-47-6

:

(5Z,8Z,11Z,14Z)-17-Hydroxy-5,8,11,14-eicosatetraenoic acid

Description:
(5Z,8Z,11Z,14Z)-17-Hydroxy-5,8,11,14-eicosatetraenoic acid, commonly known as 17-Hydroxy-eicosatetraenoic acid (17-HETE), is a polyunsaturated fatty acid derived from arachidonic acid. It is characterized by its four double bonds located at specific positions in the carbon chain, which contribute to its reactivity and biological functions. This compound is a metabolite of arachidonic acid and plays a significant role in various physiological processes, including inflammation, vascular function, and cell signaling. 17-HETE is involved in the synthesis of eicosanoids, which are signaling molecules that mediate numerous biological responses. Its hydroxyl group at the 17th carbon position enhances its interaction with specific receptors and enzymes, influencing pathways related to pain, immune response, and cardiovascular health. The compound is of interest in pharmacological research due to its potential implications in various diseases, including cancer and cardiovascular disorders. As a fatty acid derivative, it is typically found in biological membranes and can be released by the action of phospholipases.
Formula:C20H32O3
InChI:InChI=1/C20H32O3/c1-2-16-19(21)17-14-12-10-8-6-4-3-5-7-9-11-13-15-18-20(22)23/h3,5-6,8-9,11-12,14,19,21H,2,4,7,10,13,15-18H2,1H3,(H,22,23)/b5-3-,8-6-,11-9-,14-12-
InChI key:InChIKey=OPPIPPRXLIDJKN-JPURVOHMNA-N
SMILES:C(=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O)\CC(CCC)O
Synonyms:
  • 5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (5Z,8Z,11Z,14Z)-
  • 17-HETE
  • 5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (all-Z)-
  • (5Z,8Z,11Z,14Z)-17-Hydroxy-5,8,11,14-eicosatetraenoic acid
  • 17-Hydroxy-eicosatetraenoic acid
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