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CAS 128999-31-5

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citreamicin gamma

Description:
Citreamicin gamma is a macrolide antibiotic that is derived from the fermentation of certain Streptomyces species. It is characterized by its complex structure, which includes a large lactone ring and multiple sugar moieties, contributing to its biological activity. This compound exhibits antibacterial properties, particularly against Gram-positive bacteria, making it valuable in the field of microbiology and pharmaceuticals. Citreamicin gamma functions by inhibiting protein synthesis in bacterial cells, thereby preventing their growth and replication. Its mechanism of action is similar to that of other macrolides, as it binds to the 50S ribosomal subunit. Additionally, citreamicin gamma may possess antifungal and antitumor activities, although these effects are less well-studied. The compound's solubility, stability, and pharmacokinetic properties can vary, influencing its therapeutic applications. As with many antibiotics, the emergence of resistance is a concern, necessitating ongoing research to optimize its use and explore potential combinations with other antimicrobial agents.
Formula:C33H25NO12
InChI:InChI=1/C33H25NO12/c1-13(35)44-12-32(2)31(41)46-33(3)11-15-8-14-6-7-16-23(21(14)27(38)22(15)30(40)34(32)33)28(39)24-25(36)17-9-19(42-4)20(43-5)10-18(17)45-29(24)26(16)37/h6-10,38H,11-12H2,1-5H3
Synonyms:
  • citreamicin gamma
  • [1]Benzopyrano[2',3':6,7]naphth[2,1-g]oxazolo[3,2-b]isoquinoline-2,8,14,15,17(1H)-pentone, 1-[(acetyloxy)methyl]-3a,4-dihydro-16-hydroxy-11,12-dimethoxy-1,3a-dimethyl- (9CI)
  • LL E19085 gamma
  • 1-((Acetyloxy)methyl)-3a,4-dihydro-16-hydroxy-11,12-dimethoxy-1,3a-dimethyl-(1)benzopyrano(2',3':6,7)naphth(2,1-g)oxazolo(3,2-b)isoquinoline-2,8,14,15,17(1H)-pentone
  • (1)Benzopyrano(2',3':6,7)naphth(2,1-g)oxazolo(3,2-b)isoquinoline-2,8,14,15,17(1H)-pentone, 1-((acetyloxy)methyl)-3a,4-dihydro-16-hydroxy-11,12-dimethoxy-1,3a-dimethyl-
  • (16-hydroxy-11,12-dimethoxy-1,3a-dimethyl-2,8,14,15,17-pentaoxo-1,2,3a,4,8,14,15,17-octahydrochromeno[2',3':6,7]naphtho[2,1-g][1,3]oxazolo[3,2-b]isoquinolin-1-yl)methyl acetate
  • LL-E19085gamma
  • Citreamicin γ
  • Citreamicin gamma
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