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CAS 129-18-0

:

Phenylbutazone sodium

Description:
Phenylbutazone sodium, with the CAS number 129-18-0, is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is a sodium salt of phenylbutazone, which is a pyrazolone derivative. This compound is characterized by its ability to inhibit cyclooxygenase enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. Phenylbutazone sodium is typically administered in veterinary medicine, particularly for the treatment of musculoskeletal disorders in horses and other animals. It is known for its relatively high solubility in water due to the sodium salt form, which facilitates its administration. However, its use in humans has declined due to potential side effects, including gastrointestinal toxicity and the risk of blood dyscrasias. As with any medication, careful consideration of dosage and monitoring for adverse effects is essential when using phenylbutazone sodium in clinical settings.
Formula:C19H19N2O2·Na
InChI:InChI=1S/C19H19N2O2.Na/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16;/h4-13H,2-3,14H2,1H3;/q-1;+1
InChI key:InChIKey=VYOUHDLOIRJOSW-UHFFFAOYSA-N
SMILES:O=C1N(N(C(=O)[C-]1CCCC)C2=CC=CC=C2)C3=CC=CC=C3.[Na+]
Synonyms:
  • 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, ion(1-), sodium
  • 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, ion(1-), sodium (1:1)
  • 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, sodium deriv.
  • 4-Butyl-1,2-Diphenyl-3,5-Pyrazolidinedione Sodium Salt
  • 4-Butyl-1,2-Diphenylpyrazolidine-3,5-Dione
  • Butazolidine sodium
  • Diphenyldioxobutylpyrazolidine
  • Gp 26872
  • Phenyl Butazone Sodium
  • Phenyl Butazone Sodium Salt
  • See more synonyms
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