CAS 129-51-1

Ergonovine maleate

Description:

Ergonovine maleate is a pharmaceutical compound primarily used in obstetrics to manage postpartum hemorrhage and to induce uterine contractions. It is a semi-synthetic derivative of ergot alkaloids, specifically derived from the fungus Claviceps purpurea. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for injection. Its mechanism of action involves stimulating alpha-adrenergic receptors, leading to vasoconstriction and increased uterine tone. Ergonovine maleate is typically administered via intramuscular or intravenous routes, and its effects can be rapid, necessitating careful monitoring due to potential side effects such as hypertension and nausea. The compound is classified as a prescription medication and is contraindicated in certain conditions, including hypertension and cardiovascular diseases. As with all medications, it is essential to use ergonovine maleate under medical supervision to mitigate risks and ensure appropriate therapeutic outcomes.

Formula:C₁₉H₂₃N₃O₂·C₄H₄O₄

InChI:InChI=1/C19H23N3O2.C4H4O4/c1-11(10-23)21-19(24)13-6-15-14-4-3-5-16-18(14)12(8-20-16)7-17(15)22(2)9-13;5-3(6)1-2-4(7)8/h3-6,8,11,13,17,20,23H,7,9-10H2,1-2H3,(H,21,24);1-2H,(H,5,6)(H,7,8)/b;2-1-/t11?,13?,17-;/m1./s1

SMILES:C(=C\C(O)=O)\C(O)=O.CN1[C@]2(C(C=3C=4C(C2)=CNC4C=CC3)=C[C@@H](C(N[C@H](CO)C)=O)C1)[H]

Synonyms:

(8beta)-N-[(1S)-2-hydroxy-1-methylethyl]-6-methyl-9,10-didehydroergoline-8-carboxamide (2Z)-but-2-enedioate (salt)
<span class="text-smallcaps">D</span>-Ergonovine maleate
Cornocentin
Ergobasine maleate
Ergoline-8-carboxamide, 9,10-didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methyl-, (8β)-, (2Z)-2-butenedioate (1:1)
Ergoline-8-carboxamide, 9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methyl-, [8β(S)]-, (Z)-2-butenedioate (1:1) (salt)
Ergoline-8-carboxamide, 9,10-didehydro-N-[(1S)-2-hydroxy-1-methylethyl]-6-methyl-, (8β)-, (2Z)-2-butenedioate (1:1) (salt)
Ergoline-8β-carboxamide, 9,10-didehydro-N-((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt)
Ergomet
Ergometrin maleate
Ergometrine Hydrogen Maleate
Ergometrine Maleate (Controlled Chemical)
Ergometrine acid maleate
Ergometrine maleate
Ergometrinemaleate
Ergonovine hydrogen maleate
Ergotrate
Ermetrin
Ermetrine
Indolo[4,3-fg]quinoline, ergoline-8-carboxamide deriv.
N-(2-hydroxy-1-methylethyl)-6-methyl-9,10-didehydroergoline-8-carboxamide (2Z)-but-2-enedioate (salt)
NSC 93752
See more synonyms

Purity (%)

100

Found 8 products.

+ Info
Ergometrine Maleate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
Color and Shape:Neat
Ref: 61-FOR1385.00
10mg
334.00€
VAT not included
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Ergometrine Maleate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
Formula:C₁₉H₂₃N₃O₂·C₄H₄O₄
Color and Shape:Neat
Molecular weight:441.48
Ref: 86-MM1385.00
100mg
1,310.00€
VAT not included
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ERGOMETRINE MALEATE CRS - * DRUG PRECURSOR
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
ERGOMETRINE MALEATE CRS - * DRUG PRECURSOR
Formula:C₂₃H₂₇N₃O₆
Color and Shape:Powder
Molecular weight:441.477
Ref: 41-E1000000
50mg
115.00€
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ERGOMETRINE HYDROGEN MALEATE RS - * DRUG PRECURSOR
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
ERGOMETRINE HYDROGEN MALEATE RS - * DRUG PRECURSOR
Formula:C₂₃H₂₇N₃O₆
Color and Shape:Powder
Molecular weight:441.477
Ref: 41-ICRS0296
50mg
102.00€
VAT not included
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Ergometrine maleate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
Ergometrine maleate
Formula:C₁₉H₂₃N₃O₂C₄H₄O₄
Purity:97.2%
Color and Shape:Off-White
Molecular weight:441.18999
Ref: 47-405
100mg
242.00€
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Ergonovine maleate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
<p>Ergonovine maleate is a synthetic ergot alkaloid that is used as the maleate salt. It is an effective vasoconstrictor and has been shown to be useful in the diagnosis of coronary artery disease. Ergonovine maleate has also been shown to cause significant decreases in blood pressure, particularly diastolic pressure, when administered intravenously. This drug has been shown to be helpful in treating angina pectoris by constricting the coronary arteries and reducing myocardial oxygen demand. Ergonovine maleate works by blocking the enzyme system involved in the breakdown of arginine, which leads to increased levels of nitric oxide. Nitric oxide causes vasodilation and prevents platelet aggregation, leading to decreased blood pressure.</p>
Formula:C₁₉H₂₃N₃O₂•C₄H₄O₄
Purity:Min. 95%
Molecular weight:441.48 g/mol
Ref: 3D-FE16261
5mg
303.00€
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10mg
402.00€
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25mg
715.00€
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Ergonovine Maleate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
Ergometrine and its salts
Formula:C₁₉H₂₃N₃O₂·C₄H₄O₄
Color and Shape:White Yellow Light Grey Powder
Molecular weight:441.18999
Ref: 45-1240004
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Ergometrine Maleate RS
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 129-51-1
Color and Shape:White To Pale Yellow Solid Crystalline Powder
Ref: 2K-1031000021
50mg
Discontinued
Request information
Discontinued product

CAS 129-51-1

Ergonovine maleate

Ergometrine Maleate

Ref: 61-FOR1385.00

Ergometrine Maleate

Ref: 86-MM1385.00

ERGOMETRINE MALEATE CRS - * DRUG PRECURSOR

Ref: 41-E1000000

ERGOMETRINE HYDROGEN MALEATE RS - * DRUG PRECURSOR

Ref: 41-ICRS0296

Ergometrine maleate

Ref: 47-405

Ergonovine maleate

Ref: 3D-FE16261

Ergonovine Maleate

Ref: 45-1240004

Ergometrine Maleate RS

Ref: 2K-1031000021