CAS 129050-23-3

(2S)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran

Description:

(2S)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran, with the CAS number 129050-23-3, is a chemical compound characterized by its unique structural features, including a benzopyran core and an epoxide group. This compound exhibits chirality due to the presence of stereocenters, which can influence its biological activity and interactions. The fluorine atom introduces notable electronic and steric effects, potentially enhancing its reactivity and selectivity in chemical reactions. The dihydrobenzopyran structure suggests that it may participate in various chemical transformations, including nucleophilic substitutions and cycloadditions. Additionally, the presence of the oxirane ring contributes to its reactivity, making it a candidate for further functionalization. Such compounds are often of interest in medicinal chemistry due to their potential pharmacological properties, including anti-inflammatory or anticancer activities. Overall, the characteristics of this compound make it a subject of interest for further research in synthetic and medicinal chemistry.

Formula: C₁₁H₁₁FO₂

InChI: InChI=1S/C11H11FO2/c12-8-2-4-9-7(5-8)1-3-10(14-9)11-6-13-11/h2,4-5,10-11H,1,3,6H2/t10-,11-/m0/s1

InChI key: InChIKey=GVZDIJGBXSDSEP-QWRGUYRKSA-N

SMILES: FC=1C=C2C(O[C@@](CC2)([C@@]3(CO3)[H])[H])=CC1

Synonyms:

• (2S)-2-((2S)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)oxirane
• (2S)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran
• 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-(2S)-oxiranyl-, (2S)-
• 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2S)-
• 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-oxiranyl-, [S-(R*,R*)]-
• 2H-1-benzopyran, 6-fluoro-3,4-dihydro-2-oxiranyl-, (2S)-
• (2S)-6-Fluoro-2-(oxiran-2-yl)chromane

Nebivolol Impurity 16

CAS: 129050-23-3

Formula: C₁₁H₁₁FO₂

Color and Shape: Colorless Liquid

Molecular weight: 194.21

Ref: 4Z-N-2035

(2S, 2’S)-6-Fluoro-2-(2’-oxiranyl)chromane

Controlled Product

CAS: 129050-23-3

Applications (-)-Nebivolol intermediate.
References Yang, Y., et al.: J. Chem. Res., 9, 506 (2007),

Formula: C₁₁H₁₁FO₂

Color and Shape: Neat

Molecular weight: 194.2

Ref: TR-F595146

Nebivolol Impurity 27

CAS: 129050-23-3

Formula: C₁₁H₁₁FO₂

Molecular weight: 194.21

Ref: ST-EA-CP-N5058