CAS 129050-26-6

(2R)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran

Description:

(2R)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran, with the CAS number 129050-26-6, is a chemical compound that belongs to the class of benzopyrans, which are characterized by a fused benzene and pyran ring structure. This specific compound features a fluorine atom at the 6-position of the benzopyran moiety, contributing to its unique reactivity and potential biological activity. The presence of an epoxide group (oxirane) at the 2-position adds to its chemical complexity, making it a subject of interest in medicinal chemistry. The stereochemistry indicated by the (2R) and (2S) designations suggests that the compound has specific spatial arrangements that can influence its interactions with biological targets. Such compounds are often investigated for their potential pharmacological properties, including anti-inflammatory or anticancer activities. The stability, solubility, and reactivity of this compound can be influenced by its functional groups and stereochemistry, making it a valuable candidate for further research in drug development and synthetic chemistry.

Formula: C₁₁H₁₁FO₂

InChI: InChI=1S/C11H11FO2/c12-8-2-4-9-7(5-8)1-3-10(14-9)11-6-13-11/h2,4-5,10-11H,1,3,6H2/t10-,11+/m1/s1

InChI key: InChIKey=GVZDIJGBXSDSEP-MNOVXSKESA-N

SMILES: FC=1C=C2C(O[C@](CC2)([C@@]3(CO3)[H])[H])=CC1

Synonyms:

• (2S)-2-((2R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)oxirane
• 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)-
• 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-oxiranyl-, [R-(R*,S*)]-
• (2R)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran

Nebivolol Impurity 20

CAS: 129050-26-6

Formula: C₁₁H₁₁FO₂

Color and Shape: White To Off-White Solid

Molecular weight: 194.21

Ref: 4Z-N-2038

(2R, 2’S)-6-Fluoro-2-(2’-oxiranyl)chromane

Controlled Product

CAS: 129050-26-6

Applications (-)-Nebivolol intermediates.
References Yang, Y., et al.: J. Chem. Res., 9, 506 (2007),

Formula: C₁₁H₁₁FO₂

Color and Shape: Neat

Molecular weight: 194.21

Ref: TR-F595145

Nebivolol Impurity 30

CAS: 129050-26-6

Formula: C₁₁H₁₁FO₂

Molecular weight: 194.21

Ref: ST-EA-CP-N5060