CAS 129075-56-5

3,4-Dihydro-5-methyl-1(2H)-isoquinolinone

Description:

3,4-Dihydro-5-methyl-1(2H)-isoquinolinone, with the CAS number 129075-56-5, is a chemical compound that belongs to the isoquinoline family, characterized by a bicyclic structure containing a nitrogen atom. This compound features a dihydroisoquinoline framework, which is a saturated derivative of isoquinoline, and includes a methyl group at the 5-position. Its molecular structure contributes to its potential biological activity, making it of interest in medicinal chemistry. The compound is typically a solid at room temperature and may exhibit solubility in organic solvents, depending on its specific functional groups. It may also participate in various chemical reactions, such as electrophilic substitutions or reductions, due to the presence of the nitrogen atom and the double bonds in the isoquinoline ring system. The compound's properties, including melting point, boiling point, and reactivity, can vary based on its purity and the conditions under which it is handled. Overall, 3,4-Dihydro-5-methyl-1(2H)-isoquinolinone is a significant compound for research in organic synthesis and pharmacology.

Formula: C₁₀H₁₁NO

InChI: InChI=1S/C10H11NO/c1-7-3-2-4-9-8(7)5-6-11-10(9)12/h2-4H,5-6H2,1H3,(H,11,12)

InChI key: InChIKey=RLLZPXDJYADIEU-UHFFFAOYSA-N

SMILES: CC1=C2C(C(=O)NCC2)=CC=C1

Synonyms:

• 3,4-dihydro-5-methyl-1(2H)-isoquinolinone
• 5-methyl-3,4-dihydroisoquinolin-1(2H)-one
• Pd-128763
• 1(2H)-Isoquinolinone, 3,4-dihydro-5-methyl-

5-Methyl-3,4-dihydroisoquinolin-1(2H)-one

CAS: 129075-56-5

Formula: C₁₀H₁₁NO

Purity: 90%

Color and Shape: Solid

Molecular weight: 161.2004

Ref: IN-DA000YT7

5-Methyl-3,4-dihydroisoquinolin-1(2H)-one

CAS: 129075-56-5

5-Methyl-3,4-dihydroisoquinolin-1(2H)-one

Purity: 99%

Molecular weight: 161.20g/mol

Ref: 54-OR94844

5-Methyl-3,4-dihydroisoquinolin-1(2H)-one

CAS: 129075-56-5

Formula: C₁₀H₁₁NO

Purity: 90%

Color and Shape: Liquid, No data available.

Molecular weight: 161.204

Ref: 10-F228426

5-Methyl-3,4-dihydroisoquinolin-1(2H)-one

CAS: 129075-56-5

5-Methyl-3,4-dihydroisoquinolin-1(2H)-one is a detectable compound that is found in adventitia. It has been shown to have polymerase activity and can be used to inhibit restenosis following angioplasty. 5-Methyl-3,4-dihydroisoquinolin-1(2H)-one inhibits the proliferation of vascular smooth muscle cells by inhibiting the synthesis of phosphoenolpyruvate, which is an important substrate for cellular respiration. This drug also inhibits cellular proliferation and neointimal hyperplasia in a hepatoma cell line. The drug has been shown to be effective at reducing neointimal hyperplasia following angioplasty in a porcine model of vascular injury.

Formula: C₁₀H₁₁NO

Purity: Min. 95%

Molecular weight: 161.2 g/mol

Ref: 3D-EFA07556

PD-128763

CAS: 129075-56-5

PD-128763 is a poly(ADP-ribose) polymerase inhibitor exhibiting radiosensitising effects, enhancing radiation-induced cell killing in X-ray-irradiated cells.

Formula: C₁₀H₁₁NO

Color and Shape: Solid

Molecular weight: 161.20

Ref: TM-T71966