CAS 129101-54-8: Rivastigmine tartrate
Description:Rivastigmine tartrate is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and Parkinson's disease dementia. It enhances cholinergic function by increasing the levels of acetylcholine in the brain, which is crucial for memory and cognitive functions. The substance is a white to off-white crystalline powder that is soluble in water and exhibits a molecular formula that includes both carbon and nitrogen components, reflecting its organic nature. Rivastigmine tartrate is typically administered orally or transdermally, with its pharmacokinetics characterized by rapid absorption and a relatively short half-life, necessitating multiple doses throughout the day or a continuous delivery system via patches. The compound is known for its side effects, which may include gastrointestinal disturbances, dizziness, and fatigue. Its use is contraindicated in patients with certain medical conditions, and it requires careful monitoring for efficacy and safety. Overall, Rivastigmine tartrate plays a significant role in managing cognitive decline associated with neurodegenerative diseases.
Formula:C14H22N2O2·C4H6O6
InChI:InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
InChI key:InChIKey=GWHQHAUAXRMMOT-MBANBULQSA-N
SMILES:O=C(O)C(O)C(O)C(=O)O.O=C(OC1=CC=CC(=C1)C(N(C)C)C)N(C)CC
- Synonyms:
- 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (1:1)
- 3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (salt)
- Carbamic acid, N-ethyl-N-methyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
- Carbamic acid, ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl ester, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
- Carbamic acid, ethylmethyl-, 3-(1-(dimethylamino)ethyl)phenyl ester, (S)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1)
- Ena 713
- Rivastigimine tartrate
- Rivastigmine Bitartrate
- Rivastigmine hydrogen tartrate
- Rivastigmine hydrogentartrate
- See more synonyms
- Sdz-Ena 713
- Unii-9Iy2357Jpe