CAS 129121-73-9: ALPHA-CGRP (8-37) (RAT)

Description: Alpha-CGRP (8-37) is a peptide that serves as a selective antagonist of the calcitonin gene-related peptide (CGRP) receptor. It is derived from the endogenous CGRP molecule, with specific modifications that enhance its antagonistic properties. This peptide is primarily studied in the context of neurobiology and pain research, particularly for its role in migraine pathophysiology. Alpha-CGRP (8-37) has been shown to inhibit the effects of CGRP, which is involved in vasodilation and the transmission of pain signals. The substance is characterized by its ability to bind to CGRP receptors, thereby blocking the physiological effects mediated by CGRP. Its structure includes a sequence of amino acids that contribute to its receptor-binding affinity and specificity. Research involving Alpha-CGRP (8-37) often focuses on its potential therapeutic applications in treating migraine and other conditions associated with CGRP signaling. As a synthetic peptide, it is typically used in laboratory settings for experimental purposes, and its safety and efficacy are evaluated in preclinical studies.

Formula: C₁₃₈H₂₂₄N₄₂O₄₁

Synonyms:

• Cgrp 8-37 (Rat)
• H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-Nh2
• Calcitonin Gene Related Peptide (8-37) Rat
• Alpha-Calcitonin Gene-Related Peptide (8-37) (Rat)
• Vthrlagllsrsggvvkdnfvptnvgseaf-Nh2
• Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-Nh2

α-CGRP (8-37) (mouse, rat)

CAS: 129121-73-9

α-CGRP (8-37), a competitive CGRP1 receptor antagonist, exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized …

• Formula: C₁₃₈H₂₂₄N₄₂O₄₁
• Purity: 95.7%
• Color and Shape: White Lyophilisate
• Molecular weight: 3127.56

α-CGRP (8-37) (mouse, rat) trifluoroacetate salt

CAS: 129121-73-9

• Formula: C₁₃₈H₂₂₄N₄₂O₄₁
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 3127.5120

CGRP 8-37 (rat)

CAS: 129121-73-9

CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects …

• Formula: C₁₃₈H₂₂₄N₄₂O₄₁
• Purity: 99.28%
• Color and Shape: Solid
• Molecular weight: 3127.51

α-CGRP (8-37) (mouse, rat) trifluoroacetate salt

CAS: 129121-73-9

Trifluoroacetate salt

• Formula: C₁₃₈H₂₂₄N₄₂O₄₁
• Purity: Min. 95%
• Molecular weight: 3,127.51 g/mol

Calcitonin Gene Related Peptide (8-37), rat

CAS: 129121-73-9

Please enquire for more information about Calcitonin Gene Related Peptide (8-37), rat including the price, …

• Formula: C₁₃₈H₂₂₄N₄₂O₄₁
• Purity: Min. 95%
• Molecular weight: 3,127.51 g/mol