CAS 1292285-54-1

SPR inhibitor 3

CAS: 1292285-54-1

SPR inhibitor 3 blocks sepiapterin reductase, eases neuropathic pain, and lowers BH4 with high affinity (IC50: 74 nM cell-free, 5.2 μM cell-based).

Formula: C₁₄H₁₈N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 262.3

Ref: TM-T16924

SPRi 3

CAS: 1292285-54-1

SPRi 3 is a synthetic sepiapterin analogue. It has been shown to be a selective inhibitor of the enzyme aromatic L-amino acid decarboxylase (AADC) in cancer cells and has also shown some antitumour activity. SPRi 3 is able to inhibit the synthesis of monoamine neurotransmitters, which are involved in pain modulation and have been implicated in autoimmune disease pathogenesis. SPRi 3 is also able to activate cardiac tissue and relieve pain caused by inflammation or injury.

Formula: C₁₄H₁₈N₂O₃

Purity: Min. 95%

Molecular weight: 262.3 g/mol

Ref: 3D-SBC28554