CAS 129273-26-3

(3beta,5beta,12beta,14xi)-3-[2-({6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}amino)-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide

Description:

The chemical substance with the name "(3beta,5beta,12beta,14xi)-3-[2-({6-[(2,5-dioxopyrrolidin-1-yl)oxy]-6-oxohexyl}amino)-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide" and CAS number "129273-26-3" is a complex organic compound characterized by its unique structural features, including multiple hydroxyl groups and a cardenolide backbone. This compound likely exhibits biological activity due to its structural similarity to naturally occurring cardiac glycosides, which are known for their effects on cardiac function. The presence of the pyrrolidinone moiety suggests potential interactions with biological targets, possibly influencing enzyme activity or receptor binding. Its solubility and stability would depend on the functional groups present, particularly the hydroxyl and ether functionalities, which can enhance solubility in polar solvents. Additionally, the compound's stereochemistry, indicated by the specific beta and xi configurations, may play a crucial role in its pharmacological properties and interactions within biological systems. Overall, this substance represents a class of compounds with potential therapeutic applications, warranting further investigation into its biological effects and mechanisms of action.

Formula: C₃₅H₅₀N₂O₁₀

InChI: InChI=1/C35H50N2O10/c1-33-13-11-23(45-20-28(39)36-15-5-3-4-6-31(42)47-37-29(40)9-10-30(37)41)17-22(33)7-8-25-26(33)18-27(38)34(2)24(12-14-35(25,34)44)21-16-32(43)46-19-21/h16,22-27,38,44H,3-15,17-20H2,1-2H3,(H,36,39)/t22-,23+,24-,25-,26+,27-,33+,34+,35?/m1/s1

Digoxigenin NHS-ester

CAS: 129273-26-3

Digoxigenin is a fluorescent molecule that binds to the neurokinin-1 receptor. It has been used as an experimental model for cardiac tissue culture. Digoxigenin NHS-ester is a fluorescent derivative of digoxigenin that has been used to study the uptake and distribution of this compound in various tissues, including the heart. Digoxigenin NHS-ester binds to collagen and other extracellular matrix proteins and can be detected by immunofluorescence. In addition, it has been shown to stimulate growth factor release from cardiomyocytes. The fluorescence properties of digoxigenin NHS-ester can be measured using a fluorimeter with an excitation wavelength of 350 nm and emission wavelength of 450 nm. This molecule is also used as a marker for cell proliferation, because its accumulation in cells increases during cell division. The binding affinity of digoxigenin NHS-ester for neurokinin receptors is dependent on intramolecular hydrogen bonds formed between the amide

Formula: C₃₅H₅₀N₂O₁₀

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 658.78 g/mol

Ref: 3D-FD45749

(3Beta,5Beta,12Beta)-3-[2-[[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide

Controlled Product

CAS: 129273-26-3

Stability Moisture Sensitive
Applications (3β,5β,12β)-3-[2-[[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethoxy]-12,14-dihydroxycard-20(22)-enolide is a digoxin (D446575) cross-linking reagent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₃₅H₅₀N₂O₁₀

Color and Shape: Neat

Molecular weight: 658.78

Ref: TR-D486968