Seltorexant hydrochloride is a novel pharmacological compound primarily investigated for its potential use in treating insomnia and other sleep disorders. It functions as a selective orexin receptor antagonist, specifically targeting the orexin-1 and orexin-2 receptors, which play a crucial role in regulating wakefulness and sleep. The chemical structure of Seltorexant hydrochloride includes a complex arrangement of atoms that contributes to its biological activity and pharmacokinetic properties. It is typically administered in its hydrochloride salt form to enhance solubility and stability. The compound has shown promise in clinical trials, demonstrating efficacy in improving sleep onset and maintenance while exhibiting a favorable safety profile. As with many pharmaceuticals, its development involves rigorous testing for efficacy, safety, and potential side effects. Understanding its mechanism of action and pharmacodynamics is essential for optimizing its therapeutic use and minimizing adverse effects. Overall, Seltorexant hydrochloride represents a significant advancement in the pharmacotherapy of sleep disorders.

Seltorexant hydrochloride

1293284-49-7: Seltorexant hydrochloride is a novel pharmacological compound primarily investigated for its potential use in treating insomnia and other sleep disorders. It functions as a selective orexin receptor antagonist, specifically targeting the orexin-1 and orexin-2 receptors, which play a crucial role in regulating wakefulness and sleep. The chemical structure of Seltorexant hydrochloride includes a complex arrangement of atoms that contributes to its biological activity and pharmacokinetic properties. It is typically administered in its hydrochloride salt form to enhance solubility and stability. The compound has shown promise in clinical trials, demonstrating efficacy in improving sleep onset and maintenance while exhibiting a favorable safety profile. As with many pharmaceuticals, its development involves rigorous testing for efficacy, safety, and potential side effects. Understanding its mechanism of action and pharmacodynamics is essential for optimizing its therapeutic use and minimizing adverse effects. Overall, Seltorexant hydrochloride represents a significant advancement in the pharmacotherapy of sleep disorders.

Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.

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CAS 1293284-49-7

Seltorexant hydrochloride

Seltorexant hydrochloride

Ref: TM-T12877

Seltorexant hydrochloride

Ref: 3D-TBC28449