CAS 129332-29-2

rel-1,1-Dimethylethyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate

Description:

Rel-1,1-Dimethylethyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate, with CAS number 129332-29-2, is a complex organic compound characterized by its specific stereochemistry and functional groups. This substance features a heptenoate backbone, indicating the presence of a seven-carbon chain with a double bond, which contributes to its reactivity and potential biological activity. The presence of multiple hydroxyl groups suggests that it may exhibit polar characteristics, enhancing its solubility in polar solvents. The fluorophenyl and indole moieties indicate potential interactions with biological targets, making it of interest in medicinal chemistry. The stereochemical configuration (3R,5S) implies specific spatial arrangements that can influence the compound's pharmacological properties. Overall, this compound's unique structure may confer specific biological activities, making it a candidate for further research in drug development or other applications in the pharmaceutical industry.

Formula: C₂₈H₃₄FNO₄

InChI: InChI=1/C28H34FNO4/c1-18(2)30-24-9-7-6-8-23(24)27(19-10-12-20(29)13-11-19)25(30)15-14-21(31)16-22(32)17-26(33)34-28(3,4)5/h6-15,18,21-22,31-32H,16-17H2,1-5H3/b15-14+/t21-,22-/s2

InChI key: InChIKey=USGKHYXJISAYPE-QCVTZSIDNA-N

SMILES: C(=C/[C@@H](C[C@@H](CC(OC(C)(C)C)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3

Synonyms:

• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-rel-
• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, [R*,S*-(E)]-
• Fluvastatin sodium intermediate F4
• rel-1,1-Dimethylethyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoate
• tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate
• tert-Butyl(R*,S*-(E))-(±)-7-[3-(4-fluorophenyl)-1-(-1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
• tert-butyl (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
• tert-butyl (6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate

Fluvastatin Related Compound B ([R*,S*-E]-(+/-)-7-[3-(4-fluorophenyl)-1-methylethyl-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid 1,1, dimethylethyl ester)

CAS: 129332-29-2

Aromatic or modified aromatic drugs with nitrogen heter

Formula: C₂₈H₃₄FNO₄

Color and Shape: Powder

Molecular weight: 467.57

Ref: 45-1285964

6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-rel-

CAS: 129332-29-2

Formula: C₂₈H₃₄FNO₄

Color and Shape: Solid

Molecular weight: 467.5723

Ref: IN-DA000Z3B

Fluvastatin EP Impurity B (as Racemate)

Controlled Product

CAS: 129332-29-2

Formula: C₂₈H₃₄FNO₄

Color and Shape: Neat

Molecular weight: 467.57

Ref: 86-MM0676.03

tert-Butyl Fluvastatin

CAS: 129332-29-2

Impurity Fluvastatin USP Related Compound B
Applications tert-Butyl Fluvastatin (Fluvastatin USP Related Compound B) is a derivative of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);

Formula: C₂₈H₃₄FNO₄

Color and Shape: Neat

Molecular weight: 467.57

Ref: TR-B692385

Fluvastatin USP Related Compound B

CAS: 129332-29-2

Formula: C₂₈H₃₄FNO₄

Molecular weight: 467.58

Ref: ST-EA-CP-F39008