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CAS 129397-83-7

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Fmoc-Phe-ol

Description:
Fmoc-Phe-ol, or 9-fluorenylmethoxycarbonyl phenylalanine phenol, is a chemical compound commonly used in peptide synthesis and as a protecting group in organic chemistry. It features a fluorenylmethoxycarbonyl (Fmoc) group, which is a widely utilized protecting group for amines due to its stability under basic conditions and ease of removal under mild acidic conditions. The phenylalanine component contributes to its role in peptide synthesis, providing a hydrophobic aromatic side chain that can influence the properties of the resulting peptides. Fmoc-Phe-ol is typically a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. Its structure allows for selective reactions, making it valuable in the synthesis of complex molecules. Additionally, the presence of the phenolic group can impart unique reactivity, enabling further functionalization. Overall, Fmoc-Phe-ol is an important reagent in the field of medicinal chemistry and peptide research, facilitating the development of biologically active compounds.
Formula:C24H23NO3
InChI:InChI=1/C24H23NO3/c26-15-18(14-17-8-2-1-3-9-17)25-24(27)28-16-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,18,23,26H,14-16H2,(H,25,27)/t18-/m0/s1
SMILES:c1ccc(cc1)C[C@@H](CO)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • N-Fmoc-L-Phenylalaninol
  • N-Alpha-Fmoc-L-Phenylalaninol
  • N-(9-Fluorenylmethoxycarbonyl)-L-Phenylalaninol
  • Fmoc-L-Phenylalaninol
  • Fmoc-Phenylalaninol
  • Fmoc-(S)-2-Amino-3-Phenyl-1-Propanol
  • Fmoc-Dl-Phenylalaninol
  • (S)-(9H-Fluoren-9-Yl)Methyl 1-Hydroxy-3-Phenylpropan-2-Ylcar
  • 9H-Fluoren-9-Ylmethyl [(1S)-1-Benzyl-2-Hydroxyethyl]Carbamate
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