CAS 129401-88-3: 1-(4-Phenyl-1-piperazinyl)-2-propen-1-one

Description: 1-(4-Phenyl-1-piperazinyl)-2-propen-1-one, also known by its CAS number 129401-88-3, is an organic compound characterized by its unique structure that includes a piperazine ring and an α,β-unsaturated carbonyl group. This compound typically exhibits properties associated with both piperazine derivatives and α,β-unsaturated ketones, which may include potential biological activity. The presence of the phenyl group contributes to its lipophilicity, potentially enhancing its ability to cross biological membranes. The compound may engage in various chemical reactions, such as nucleophilic addition or Michael addition, due to the electrophilic nature of the carbonyl group. Its structural features suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting neurological or psychiatric conditions, given the known pharmacological properties of piperazine derivatives. However, specific biological activity, toxicity, and pharmacokinetic properties would require further investigation through empirical studies.

Formula: C₁₃H₁₆N₂O

InChI: InChI=1S/C13H16N2O/c1-2-13(16)15-10-8-14(9-11-15)12-6-4-3-5-7-12/h2-7H,1,8-11H2

InChI key: InChIKey=RHLXKNKGQYNPCQ-UHFFFAOYSA-N

SMILES: O=C(C=C)N1CCN(C=2C=CC=CC2)CC1

Synonyms:

• N-Acryloyl-N′-phenylpiperazine
• 2-Propen-1-one, 1-(4-phenyl-1-piperazinyl)-
• 1-(4-Phenyl-piperazine-1-yl)-propenone
• 1-(4-Phenyl-1-piperazinyl)-2-propen-1-one
• Piperazine, 1-(1-oxo-2-propenyl)-4-phenyl-

2-Propen-1-one, 1-(4-phenyl-1-piperazinyl)-

CAS: 129401-88-3

• Formula: C₁₃H₁₆N₂O
• Molecular weight: 216.2789