PACAP-38 free acid, or Pituitary Adenylate Cyclase-Activating Polypeptide, is a neuropeptide that plays a crucial role in various physiological processes, including neuroprotection, neurotransmission, and regulation of circadian rhythms. It is composed of 38 amino acids and is known for its ability to activate adenylate cyclase, leading to increased levels of cyclic AMP in target cells. This peptide exhibits a range of biological activities, including vasodilation, modulation of immune responses, and involvement in stress responses. PACAP-38 is also implicated in the regulation of hormone secretion and has neurotrophic effects, promoting neuronal survival and growth. The free acid form of PACAP-38 is typically used in research settings to study its receptor interactions and physiological effects. Its stability and solubility in aqueous solutions make it suitable for various experimental applications. Overall, PACAP-38 free acid is a significant molecule in neurobiology and endocrinology, with potential therapeutic implications in conditions such as neurodegenerative diseases and stress-related disorders.

PACAP-38 free acid

129405-61-4: PACAP-38 free acid, or Pituitary Adenylate Cyclase-Activating Polypeptide, is a neuropeptide that plays a crucial role in various physiological processes, including neuroprotection, neurotransmission, and regulation of circadian rhythms. It is composed of 38 amino acids and is known for its ability to activate adenylate cyclase, leading to increased levels of cyclic AMP in target cells. This peptide exhibits a range of biological activities, including vasodilation, modulation of immune responses, and involvement in stress responses. PACAP-38 is also implicated in the regulation of hormone secretion and has neurotrophic effects, promoting neuronal survival and growth. The free acid form of PACAP-38 is typically used in research settings to study its receptor interactions and physiological effects. Its stability and solubility in aqueous solutions make it suitable for various experimental applications. Overall, PACAP-38 free acid is a significant molecule in neurobiology and endocrinology, with potential therapeutic implications in conditions such as neurodegenerative diseases and stress-related disorders.

<p>PACAP (1-38) free acid, an endogenous neuropeptide, potently modulates gastrointestinal and neuroendocrine functions.</p>

CAS 129405-61-4

PACAP-38 free acid

PACAP (1-38) free acid

Ref: TM-T81572