CAS 1294481-82-5

9-[(2R)-3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-9H-purin-2-amine

Description:

The chemical substance known as "9-[(2R)-3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-9H-purin-2-amine" is a complex nucleoside analog characterized by its structural components, which include a purine base and a modified sugar moiety. The presence of a 6-chloro substitution on the purine ring and multiple chlorobenzoyl groups on the sugar enhances its potential for biological activity, particularly in antiviral or anticancer applications. The fluorine atom in the sugar moiety contributes to its stability and may influence its interaction with biological targets. This compound is likely to exhibit unique pharmacological properties due to its structural modifications, which can affect its binding affinity and metabolic stability. As a nucleoside analog, it may interfere with nucleic acid synthesis, making it a candidate for therapeutic exploration in diseases where nucleic acid metabolism is disrupted. Its specific characteristics, including solubility, stability, and reactivity, would be determined through empirical studies and characterization techniques.

Formula: C₂₅H₁₉Cl₃FN₅O₅

InChI: InChI=1S/C25H19Cl3FN5O5/c1-25(29)18(39-22(36)13-4-8-15(27)9-5-13)16(10-37-21(35)12-2-6-14(26)7-3-12)38-23(25)34-11-31-17-19(28)32-24(30)33-20(17)34/h2-9,11,16,18,23H,10H2,1H3,(H2,30,32,33)/t16-,18-,23-,25-/m1/s1

InChI key: InChIKey=CWRGPCWFCOZJTQ-NMRNUDPRSA-N

SMILES: C[C@]1(F)[C@H](N2C=3C(N=C2)=C(Cl)N=C(N)N3)O[C@H](COC(=O)C4=CC=C(Cl)C=C4)[C@H]1OC(=O)C5=CC=C(Cl)C=C5

Synonyms:

• 9H-Purin-2-amine, 9-[(2R)-3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-
• 9-[(2R)-3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-9H-purin-2-amine
• (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate
• ATP-Chloronucleoside
• 9-[(2R)-3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-beta-D-erythro-pentofuranosyl]-6-chloro-9H-purin-2-amine
• (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-(((4-chlorobenzoyl)oxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl 4-chlorobenzoate

9H-Purin-2-amine, 9-[(2R)-3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-

CAS: 1294481-82-5

Formula: C₂₅H₁₉Cl₃FN₅O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 594.8063

Ref: IN-DA000Z4R

(2R,3R,4R,5R)-5-(2-Amino-6-Chloro-9H-Purin-9-Yl)-2-(((4-Chlorobenzoyl)Oxy)Methyl)-4-Fluoro-4-Methyltetrahydrofuran-3-Yl 4-Chlorobenzoate

CAS: 1294481-82-5

(2R,3R,4R,5R)-5-(2-Amino-6-Chloro-9H-Purin-9-Yl)-2-(((4-Chlorobenzoyl)Oxy)Methyl)-4-Fluoro-4-Methyltetrahydrofuran-3-Yl 4-Chlorobenzoate

Purity: 98%

Molecular weight: 594.81g/mol

Ref: 54-PC104928

(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate

CAS: 1294481-82-5

Purity: 97%

Molecular weight: 594.8099976

Ref: 10-F602830