CAS 129461-18-3

2-N-(4-(1-azitrifluoroethyl)benzoyl)-1,3-bis-(mannos-4-yloxy)-2-propylamine

Description:

2-N-(4-(1-azitrifluoroethyl)benzoyl)-1,3-bis-(mannos-4-yloxy)-2-propylamine, with CAS number 129461-18-3, is a complex organic compound characterized by its unique structural features, which include a benzoyl group, a propylamine moiety, and multiple mannosyl units. The presence of the trifluoroethyl group suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the influence of fluorine on biological activity and lipophilicity. The mannosyl units may enhance the compound's interaction with biological systems, potentially facilitating targeted delivery or recognition by specific receptors. This compound's synthesis and characterization would involve advanced organic chemistry techniques, including NMR spectroscopy, mass spectrometry, and possibly chromatography for purification. Its solubility, stability, and reactivity would be influenced by the functional groups present, making it a subject of interest for further research in drug development and bioconjugation strategies. Overall, this compound exemplifies the intricate design often found in bioactive molecules.

Formula: C₂₄H₃₂F₃N₃O₁₃

InChI: InChI=1/C24H32F3N3O13/c25-24(26,27)23(29-30-23)12-3-1-11(2-4-12)22(41)28-13(9-42-20(16(37)7-33)18(39)14(35)5-31)10-43-21(17(38)8-34)19(40)15(36)6-32/h1-6,13-21,33-40H,7-10H2,(H,28,41)/t14-,15-,16-,17-,18-,19-,20-,21-/m1/s1

SMILES: c1cc(ccc1C(=O)NC(CO[C@H]([C@@H](CO)O)[C@@H]([C@@H](C=O)O)O)CO[C@H]([C@@H](CO)O)[C@@H]([C@@H](C=O)O)O)C1(C(F)(F)F)N=N1

Synonyms:

• 2-N-4-(1-Azi-2,2,2-trifluoroethyl)benzoyl-1,3-bis(D-mannos-4-yloxy)-2-propylamine
• Atb-bmpa
• D-Mannose, 4,4'-O-(2-((4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoyl)amino)-1,3-propanediyl)bis-
• N-(1,3-bis{[(2R,3R,4R,5S)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl]oxy}propan-2-yl)-4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzamide (non-preferred name)

D-Mannose, 4,4'-O-[2-[[4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoyl]amino]-1,3-propanediyl]bis-

CAS: 129461-18-3

Formula: C₂₄H₃₂F₃N₃O₁₃

Color and Shape: Solid

Molecular weight: 627.5184

Ref: IN-DA000Z5U

2-N-[4-(1-Azitrifluoroethyl)benzoyl]-1,3-bis-(D-mannos-4-yloxy)-2-propylamine

CAS: 129461-18-3

Ref: 7W-GC0296

2-N-[4-(1-Azitrifluoroethyl)benzoyl]-1,3-bis-(D-mannos -4-yloxy)-2-propylamine

Controlled Product

CAS: 129461-18-3

Stability Hygroscopic
Applications Used as an exofacial probe for the human erythrocyte glucose transport system. The compound is impermeable and photolabeling can be confined to the discrete plasma membrane pool of glucose transporters.
References Holman, G.D., et al.: J. Biol. Chem., 265, 30, 18172 (1990), Holman, G.D., et al.: Biochem. J., 269, 615 (1990)

Formula: C₂₄H₃₂F₃N₃O₁₃

Color and Shape: Neat

Molecular weight: 627.52

Ref: TR-A927500

ATB-BMPA

CAS: 129461-18-3

Photoaffinity reagent for glucose transporters; cell-impermeant

Formula: C₂₄H₃₂F₃N₃O₁₃

Purity: Min. 95%

Molecular weight: 627.52 g/mol

Ref: 3D-EA18115