CAS 129580-63-8

Satraplatin

Description:

Satraplatin is a platinum-based chemotherapeutic agent that belongs to the class of alkylating agents. It is characterized by its ability to form DNA cross-links, which disrupts the replication and transcription processes in cancer cells, ultimately leading to cell death. Satraplatin is notable for its oral bioavailability, which distinguishes it from many other platinum compounds that are typically administered intravenously. The compound is primarily investigated for its efficacy against various solid tumors, including prostate cancer, particularly in cases resistant to conventional therapies. Its mechanism of action involves the activation of the drug within the cellular environment, allowing it to bind to DNA and interfere with cellular functions. Additionally, Satraplatin has been studied for its potential to overcome resistance mechanisms that limit the effectiveness of other platinum-based drugs. While it has shown promise in clinical trials, its overall therapeutic profile, including efficacy and safety, continues to be evaluated in ongoing research.

Formula: C₁₀H₂₂Cl₂N₂O₄Pt

InChI: InChI=1S/C6H13N.2C2H4O2.2ClH.H3N.Pt/c7-6-4-2-1-3-5-6;2*1-2(3)4;;;;/h6H,1-5,7H2;2*1H3,(H,3,4);2*1H;1H3;/q;;;;;;+4/p-4

InChI key: InChIKey=CKNPWBAXEKSCRG-UHFFFAOYSA-J

SMILES: [Pt+4]([NH2]C1CCCCC1)([O-]C(C)=O)([O-]C(C)=O)([Cl-])([Cl-])[NH3]

Synonyms:

• Bis(acetato-O)amminedichloro(cyclohexanamine)-pt
• Bms 182751
• Bmy 45594
• Cyclohexanamine, platinum complex
• Jm 216
• POplat
• Platinum (lV) cis-dichloro-trans-bis(acetato-O)ammine(cyclohexanamine)
• Platinum(4+) Chloride Acetate Cyclohexanamine Ammoniate (1:2:2:1:1)
• Platinum, bis(acetato-O)amminedichloro(cyclohexanamine)-, (OC-6-43)-
• Platinum, bis(acetato-κO)amminedichloro(cyclohexanamine)-, (OC-6-43)-
• Satraplatin

Platinum, bis(acetato-κO)amminedichloro(cyclohexanamine)-, (OC-6-43)- (9CI)

CAS: 129580-63-8

Formula: C₁₀H₂₂Cl₂N₂O₄Pt

Purity: 98%

Molecular weight: 500.2767

Ref: IN-DA000Z8P

Satraplatin

CAS: 129580-63-8

Satraplatin

Purity: ≥95%

Molecular weight: 500.28g/mol

Ref: 54-BUP01161

Satraplatin

CAS: 129580-63-8

Formula: C₁₀H₂₂Cl₂N₂O₄Pt

Purity: ≥ 98.0%

Color and Shape: White to light yellow powder

Molecular weight: 500.28

Ref: 7W-GP7844

Satraplatin

CAS: 129580-63-8

Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical

Formula: C₁₀H₂₂Cl₂N₂O₄Pt

Purity: 98.25%

Color and Shape: Solid

Molecular weight: 500.28

Ref: TM-T7221

Satraplatin

CAS: 129580-63-8

Platinum-based chemotherapeutic agent

Formula: C₁₀H₂₂Cl₂N₂O₄Pt

Purity: Min. 95%

Color and Shape: Slightly Yellow Powder

Molecular weight: 500.28 g/mol

Ref: 3D-FS65158