CAS 129612-87-9

Miproxifene

Description:

Miproxifene is a synthetic compound classified as a selective estrogen receptor modulator (SERM). It is primarily known for its potential applications in the treatment of hormone-dependent conditions, particularly in breast cancer therapy. Miproxifene exhibits both estrogenic and anti-estrogenic properties, depending on the target tissue, which allows it to modulate estrogen activity effectively. The compound has a unique chemical structure that contributes to its ability to bind selectively to estrogen receptors, influencing gene expression and cellular responses. Miproxifene's pharmacological profile suggests it may help in reducing the proliferation of estrogen-sensitive tumors while minimizing side effects associated with traditional estrogen therapies. Additionally, its safety and efficacy profile is an area of ongoing research, particularly in the context of its long-term use and potential benefits in other estrogen-related disorders. As with any pharmaceutical agent, understanding its mechanism of action, pharmacokinetics, and potential interactions with other medications is crucial for its therapeutic application.

Formula: C₂₉H₃₅NO₂

InChI: InChI=1S/C29H35NO2/c1-6-28(23-9-7-22(8-10-23)21(2)3)29(24-11-15-26(31)16-12-24)25-13-17-27(18-14-25)32-20-19-30(4)5/h7-18,21,31H,6,19-20H2,1-5H3/b29-28-

InChI key: InChIKey=FVVPWVFWOOMXEZ-ZIADKAODSA-N

SMILES: C(=C(/CC)\C1=CC=C(C(C)C)C=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=C(O)C=C3

Synonyms:

• (Z)-alpha-(p-(2-(Dimethylamino)ethoxy)phenyl)-alpha'-ethyl-4'-isopropyl-4-stilbenol
• 2-Oh-Dm-Dp
• 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-[4-(1-methylethyl)phenyl]-1-buten-1-yl]phenol
• 4-{(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-[4-(1-methylethyl)phenyl]but-1-en-1-yl}phenol
• DP-Tat-59
• Miproxifene
• Miproxifene [INN]
• Phenol, 4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-(4-(1-methyletthyl)phenyl)-1-butenyl)-, (Z)-
• Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-[4-(1-methylethyl)phenyl]-1-buten-1-yl]-
• Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-[4-(1-methylethyl)phenyl]-1-butenyl]-
• Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-[4-(1-methylethyl)phenyl]-1-butenyl]-, (Z)-
• Unii-Bgj4Z7930W

Miproxifene

Controlled Product

CAS: 129612-87-9

Applications Miproxifene is an active metabolite of TAT-59 against human breast cancer.
References Toko, T., et al.: Cancer Chemo. Pharm., 39, 390 (1997); Matsunaga, Y., et al.: Chem. Pharm. Bull., 42, 2582 (1994)

Formula: C₂₉H₃₅NO₂

Color and Shape: Neat

Molecular weight: 429.59

Ref: TR-M350000

Miproxifene

Controlled Product

CAS: 129612-87-9

Miproxifene is a potent anticancer drug that has been shown to induce apoptosis and inhibit cell cycle progression in human cancer cells. This drug has been extensively studied in Chinese hamster ovary (CHO) cells and has demonstrated significant activity against various types of cancer, including leukemia. Miproxifene acts as a protein inhibitor and has been found to be effective against several tumor cell lines. It is a promising medicinal compound for the treatment of cancer, with potential applications in both chemotherapy and radiation therapy. Miproxifene is excreted primarily through urine and is well-tolerated by patients. Its use as an anticancer agent holds great promise for the future of cancer treatment.

Formula: C₂₉H₃₅NO₂

Purity: Min. 95%

Molecular weight: 429.6 g/mol

Ref: 3D-EFA61287