CAS 1296162-15-6
:Dabigatran 3-O-acylglucuronide metabolite
Description:
Dabigatran 3-O-acylglucuronide is a metabolite of the anticoagulant drug dabigatran, which is primarily used for the prevention and treatment of thromboembolic disorders. This metabolite is formed through the conjugation of dabigatran with glucuronic acid, a process that enhances its solubility and facilitates excretion. Characteristically, dabigatran 3-O-acylglucuronide exhibits increased polarity compared to its parent compound, which may influence its pharmacokinetics and pharmacodynamics. The compound is typically analyzed using techniques such as liquid chromatography coupled with mass spectrometry (LC-MS) to assess its presence and concentration in biological samples. Its role in the overall metabolism of dabigatran is significant, as it may contribute to the drug's efficacy and safety profile. Understanding the characteristics of this metabolite is crucial for evaluating the therapeutic effects and potential side effects associated with dabigatran therapy. As with many metabolites, the specific biological activity and interactions of dabigatran 3-O-acylglucuronide may differ from those of the parent drug, necessitating further research to elucidate its clinical implications.
Formula:C31H33N7O9
Synonyms:- Dabigatran 3-O-acylglucuronide metabolite Q: What is the CAS Number of
- Dabigatran 3-O-acylglucuronide metaboliteQ: What is
- Dabigatran 3-O-acylglucuronide metabolite
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