CAS 129618-40-2

Nevirapine

Description:

Nevirapine is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It belongs to the class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs), which function by inhibiting the reverse transcriptase enzyme, thereby preventing viral replication. Nevirapine is characterized by its relatively low molecular weight and a specific chemical structure that includes a pyridine ring, contributing to its pharmacological activity. The substance is typically administered orally and is known for its rapid absorption and metabolism, primarily in the liver. Nevirapine is often used in combination with other antiretroviral agents to enhance therapeutic efficacy and reduce the risk of resistance development. Common side effects may include rash, liver toxicity, and gastrointestinal disturbances. Due to its potential for drug interactions, careful monitoring is essential when prescribed alongside other medications. Overall, Nevirapine plays a significant role in HIV treatment regimens, particularly in resource-limited settings, due to its affordability and effectiveness.

Formula: C₁₅H₁₄N₄O

InChI: InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)

InChI key: InChIKey=NQDJXKOVJZTUJA-UHFFFAOYSA-N

SMILES: CC1=C2C(N(C=3C(C(=O)N2)=CC=CN3)C4CC4)=NC=C1

Synonyms:

• 11-Cyclopropyl-4-methylDipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
• 11-Cyclopropyl-5,11-Dihydro-4-Methyl-6H-Dipyrido[3,2-B',3'-E][1,4]Diazepin-6-One
• 11-Cyclopropyl-5,11-Dihydro-4-Methyl-6H-Dipyrido[3,2-B:2',3'-E][1,4]Diazepin-6-One
• 11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
• 11-cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
• 5-Cyclopropyl-9-Methyl-5,10-Dihydro-4,5,6,10-Tetraaza-Dibenzo[A,D]Cyclohepten-11-One
• 6H-Dipyrido[3,2-B:2',3'-E][1,4]Diazepin-6-One, 11-Cyclopropyl-5,11-Dihydro-4-Methyl-
• 6H-Dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-
• Bi-Rg 587
• NSC 641530
• Nevarapine
• Nevirapine(Nvp)
• Novirapine
• Viramune

Nevirapine

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 266.30

Ref: 3B-N0922

Nevirapine Anhydrous

CAS: 129618-40-2

Color and Shape: Neat

Ref: 61-FOR1146.00

NEVIRAPINE (ANHYDROUS) CRS

CAS: 129618-40-2

NEVIRAPINE (ANHYDROUS) CRS

Formula: C₁₅H₁₄N₄O

Color and Shape: White. Powder.

Molecular weight: 266.2979

Ref: 41-Y0000520

Nevirapine

CAS: 129618-40-2

Nevirapine

Formula: C₁₅H₁₄N₄O

Purity: 99.9%

Color and Shape: Light Yellow

Molecular weight: 266.11676

Ref: 47-1270

NEVIRAPINE RS

CAS: 129618-40-2

NEVIRAPINE RS

Formula: C₁₅H₁₄N₄O

Molecular weight: 266.2979

Ref: 41-ICRS1412

NEVIRAPINE FOR PEAK IDENTIFICATION CRS

CAS: 129618-40-2

NEVIRAPINE FOR PEAK IDENTIFICATION CRS

Formula: C₁₅H₁₄N₄O

Molecular weight: 266.2979

Ref: 41-Y0000521

Nevirapine Anhydrous

CAS: 129618-40-2

Anti-infective agents, nesoi

Formula: C₁₅H₁₄N₄O

Color and Shape: White Powder

Molecular weight: 266.11676

Ref: 45-1460703

Nevirapine

CAS: 129618-40-2

Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.

Formula: C₁₅H₁₄N₄O

Purity: 99.58% - 99.59%

Color and Shape: White Or Off-White Crystalline Powder

Molecular weight: 266.3

Ref: TM-T1595

Nevirapine

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.2979

Ref: IN-DA0080HY

Nevirapine

CAS: 129618-40-2

Nevirapine

Purity: 98%

Molecular weight: 266.3g/mol

Ref: 54-OR1030257

Nevirapine

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Color and Shape: White To Off-White Solid

Molecular weight: 266.31

Ref: 4Z-N-221

Nevirapine

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Purity: 98.0 - 102.0 % (dried basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 266.30

Ref: 7W-GP9839

Nevirapine

CAS: 129618-40-2

Nevirapine

Purity: ≥98%

Molecular weight: 266.3g/mol

Ref: 54-BUP14481

Nevirapine

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Color and Shape: Neat

Molecular weight: 266.30

Ref: 04-C15505500

Nevirapine 100 µg/mL in Acetonitrile

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Color and Shape: Single Solution

Molecular weight: 266.30

Ref: 04-A15505500AL-100

Nevirapine

CAS: 129618-40-2

Color and Shape: Neat

Ref: 86-MM1146.00

Nevirapine-d5

CAS: 129618-40-2

Formula: C₁₅H₉N₄OD₅

Molecular weight: 271.34

Ref: 4Z-N-222

Nevirapine

CAS: 129618-40-2

Applications A potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.
References Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991), Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993), Guay, L.A., et al.: Lancet, 354, 795 (1999),

Formula: C₁₅H₁₄N₄O

Color and Shape: Light Yellow

Molecular weight: 266.30

Ref: TR-N391275

Nevirapine

CAS: 129618-40-2

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with action on HIV reverse transcriptase to block viral replication and is used for treating HIV/AIDS in combination therapies.

Formula: C₁₅H₁₄N₄O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 266.3 g/mol

Ref: 3D-NN15304

2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one

CAS: 129618-40-2

Formula: C₁₅H₁₄N₄O

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 266.304

Ref: 10-F358078