CAS 129722-25-4
:DEHYDRO ARIPIPRAZOLE
Description:
Dehydroaripiprazole is a chemical compound that serves as a metabolite of aripiprazole, an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. It is characterized by its unique molecular structure, which includes a piperazine ring and a quinolinone moiety, contributing to its pharmacological properties. Dehydroaripiprazole exhibits partial agonist activity at dopamine D2 receptors and serotonin 5-HT1A receptors, while acting as an antagonist at 5-HT2A receptors. This profile is significant in modulating neurotransmitter activity in the brain, which can help alleviate symptoms of various psychiatric conditions. The compound is typically found in the form of a white to off-white powder and is soluble in organic solvents. Its stability and reactivity are influenced by environmental factors such as pH and temperature. As a metabolite, dehydroaripiprazole plays a role in the overall pharmacokinetics of aripiprazole, impacting its efficacy and safety profile in clinical use.
Formula:C23H25Cl2N3O2
Synonyms:- 7-[4-[4-(2,3-Dichlorophenyl)-1-Piperazinyl]Butoxy]-2(1H)-Quinolinone
- 2(1H)-Quinolinone,7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-
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Found 13 products.
Aripiprazole Related Compound G (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}quinolin-2(1H)-one)
CAS:Lactams, nesoiFormula:C23H25Cl2N3O2Color and Shape:White Light Yellow Crystalline PowderMolecular weight:445.132387-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-2(1H)-quinolinone
CAS:Formula:C23H25Cl2N3O2Purity:97%Color and Shape:SolidMolecular weight:446.3695Aripiprazole EP Impurity E (Aripiprazole USP Related Compound G, Dehydro Aripiprazole)
CAS:Formula:C23H25Cl2N3O2Color and Shape:Off-White SolidMolecular weight:446.37Aripiprazole EP Impurity E-d8 (Aripiprazole USP Related Compound G-d8, Dehydro Aripiprazole-d8)
CAS:Formula:C23H17D8Cl2N3O2Color and Shape:White To Off-White SolidMolecular weight:454.42Dehydroaripiprazole
CAS:Dehydroaripiprazole (DM-14857), aripiprazole's active metabolite, is formed by CYP3A4 and CYP2D6, with similar antipsychotic effects.Formula:C23H25Cl2N3O2Purity:98.7%Color and Shape:SolidMolecular weight:446.37Dehydro Aripiprazole
CAS:Controlled Product<p>Impurity Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G<br>Applications Dehydro Aripiprazole (Aripiprazole EP Impurity E; Aripiprazole USP Related Compound G) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Zeidan, T.A., et al.: Crystal. Growth. Design., 13, 2036 (2013); Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012); Chen, X., et al.: J. Med. Chem., 55, 7141 (2012);<br></p>Formula:C23H25Cl2N3O2Color and Shape:Off-WhiteMolecular weight:446.37Aripiprazole EP Impurity E
CAS:Aripiprazole EP Impurity E is a potential impurity of aripiprazole, which is an antipsychotic drug. It has been detected as a major impurity in the drug. Aripiprazole EP Impurity E has been found to be present in human plasma and it is thought that this impurity may have pharmacological effects on humans similar to those of aripiprazole. The detection of this impurity has been achieved using LC-MS/MS methods. This method can be used for wastewater treatment due to the matrix effect of nitrogen atoms. Aripiprazole EP Impurity E may have significant implications in the diagnosis, prevention, and treatment of obesity and other metabolic disorders.Formula:C23H25Cl2N3O2Purity:Min. 95%Molecular weight:446.37 g/mol
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