2-Acetamido-2,4-dideoxy-4-fluoro-D-galactopyranose is a synthetic carbohydrate derivative that belongs to the class of amino sugars. This compound features a galactopyranose ring structure, which is a six-membered cyclic form of galactose, modified by the presence of an acetamido group and a fluorine atom at specific positions. The acetamido group contributes to its solubility and biological activity, while the fluorine substitution can enhance its stability and alter its interaction with biological targets. This compound is of interest in medicinal chemistry and biochemistry, particularly for its potential applications in drug development and as a tool for studying carbohydrate-protein interactions. Its unique structural modifications may influence its reactivity, binding affinity, and overall biological properties. As with many carbohydrate derivatives, the stereochemistry and functional groups play a crucial role in determining its chemical behavior and potential applications in various fields, including pharmaceuticals and glycoscience.

2-ACETAMIDO-2,4-DIDEOXY-4-FLUORO-D-GALACTOPYRANOSE

129728-92-3: 2-Acetamido-2,4-dideoxy-4-fluoro-D-galactopyranose is a synthetic carbohydrate derivative that belongs to the class of amino sugars. This compound features a galactopyranose ring structure, which is a six-membered cyclic form of galactose, modified by the presence of an acetamido group and a fluorine atom at specific positions. The acetamido group contributes to its solubility and biological activity, while the fluorine substitution can enhance its stability and alter its interaction with biological targets. This compound is of interest in medicinal chemistry and biochemistry, particularly for its potential applications in drug development and as a tool for studying carbohydrate-protein interactions. Its unique structural modifications may influence its reactivity, binding affinity, and overall biological properties. As with many carbohydrate derivatives, the stereochemistry and functional groups play a crucial role in determining its chemical behavior and potential applications in various fields, including pharmaceuticals and glycoscience.

<p>2-Acetamido-2,4-dideoxy-4-fluoro-D-galactopyranose (2ADF) is a synthetic ligand that binds to selectins, which are receptors expressed on the surface of cells. 2ADF has been shown to have a pharmacological effect in inhibiting inflammatory diseases by binding to and blocking the function of selectins. This drug has also been shown to inhibit leukocyte trafficking and chemotaxis by preventing the binding of selectins with their ligands, galectin 1 or galectin 3. 2ADF does not bind to glycan structures found on the cell membrane, but instead binds to glycan structures found on the surfaces of cells.</p>

CAS 129728-92-3

2-ACETAMIDO-2,4-DIDEOXY-4-FLUORO-D-GALACTOPYRANOSE

2-Acetamido-2,4-dideoxy-4-fluoro-D-galactopyranose

Ref: 3D-MA92054